Arie Struyk
Affiliations: | Mereck Labs, Boston, MA, United States |
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"Arie Struyk"Mean distance: 15.86 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Stephen C. Cannon | post-doc | 1999-2004 | Harvard Medical School and Massachusetts General Hospital |
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Publications
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| Wu F, Mi W, Fu Y, et al. (2016) Mice with an NaV1.4 sodium channel null allele have latent myasthenia, without susceptibility to periodic paralysis. Brain : a Journal of Neurology |
| Wu F, Mi W, Hernández-Ochoa EO, et al. (2012) A calcium channel mutant mouse model of hypokalemic periodic paralysis. The Journal of Clinical Investigation. 122: 4580-91 |
| Wu F, Mi W, Burns DK, et al. (2011) A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis. The Journal of Clinical Investigation. 121: 4082-94 |
| Kudryashova E, Struyk A, Mokhonova E, et al. (2011) The common missense mutation D489N in TRIM32 causing limb girdle muscular dystrophy 2H leads to loss of the mutated protein in knock-in mice resulting in a Trim32-null phenotype. Human Molecular Genetics. 20: 3925-32 |
| Francis DG, Rybalchenko V, Struyk A, et al. (2011) Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia. Neurology. 76: 1635-41 |
| Fu Y, Struyk A, Markin V, et al. (2011) Gating behaviour of sodium currents in adult mouse muscle recorded with an improved two-electrode voltage clamp. The Journal of Physiology. 589: 525-46 |
| Francis D, Struyk A, Cannon SC. (2010) Arginine Mutations in the S4 VSD of NaV1.4 Associated with Hypokalemic Periodic Paralysis, But Not with Paramyotonia, Create a Gating Pore Conductance Biophysical Journal. 98: 111a |
| Struyk A, Cannon SC. (2009) Gating Pore Currents from S4 Mutations of NaV1.4: A Common Pathomechanism in Hypokalemic Periodic Paralysis Biophysical Journal. 96: 203a |
| Struyk AF, Markin VS, Francis D, et al. (2008) Gating pore currents in DIIS4 mutations of NaV1.4 associated with periodic paralysis: saturation of ion flux and implications for disease pathogenesis. The Journal of General Physiology. 132: 447-64 |
| Struyk AF, Cannon SC. (2008) Paradoxical depolarization of BA2+- treated muscle exposed to low extracellular K+: insights into resting potential abnormalities in hypokalemic paralysis. Muscle & Nerve. 37: 326-37 |