Tomas Björklund

Brain Repair and Imaging in Neural Systems Lund University, Lund, Skåne län, Sweden 
Parkinson's Disease, Gene therapy
"Tomas Björklund"

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Björklund T. (2016) Expression of Multiple Functional RNAs or Proteins from One Viral Vector. Methods in Molecular Biology (Clifton, N.J.). 1382: 41-56
Holmqvist S, Chutna O, Bousset L, et al. (2014) Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats. Acta Neuropathologica. 128: 805-20
Aldrin-Kirk P, Davidsson M, Holmqvist S, et al. (2014) Novel AAV-based rat model of forebrain synucleinopathy shows extensive pathologies and progressive loss of cholinergic interneurons. Plos One. 9: e100869
Cederfjäll E, Nilsson N, Sahin G, et al. (2013) Continuous DOPA synthesis from a single AAV: dosing and efficacy in models of Parkinson's disease. Scientific Reports. 3: 2157
Hansen C, Björklund T, Petit GH, et al. (2013) A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP. Neurobiology of Disease. 56: 145-55
Ulusoy A, Björklund T, Buck K, et al. (2012) Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons. Neurobiology of Disease. 47: 367-77
Cederfjäll E, Sahin G, Kirik D, et al. (2012) Design of a single AAV vector for coexpression of TH and GCH1 to establish continuous DOPA synthesis in a rat model of Parkinson's disease. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1315-26
Björklund A, Björklund T. (2011) Gene therapy for Parkinson's disease shows promise. Science Translational Medicine. 3: 79ed1
Hult S, Soylu R, Björklund T, et al. (2011) Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits. Cell Metabolism. 13: 428-39
Björklund T, Cederfjäll EA, Kirik D. (2010) Gene therapy for dopamine replacement. Progress in Brain Research. 184: 221-35
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