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Janet M. Thornton

Affiliations: 
European Bioinformatics Institute, Hinxton, England, United Kingdom 
Area:
protein structures and sequences using computational approaches
Website:
http://www.ebi.ac.uk/about/people/janet-thornton
Google:
"Janet M. Thornton"
Bio:

http://www.nasonline.org/member-directory/members/20004894.html
PNAS Profile of Janet M. Thornton

Cross-listing: Chemistry Tree

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Parents

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Peter M. Bayley grad student 1973 National Institute for Medical Research
David Chilton Phillips post-doc 1973-1979 Oxford
Tom Blundell research scientist 1979-1990 Birkbeck College

Children

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Julia Fischer grad student European Bioinformatics Institute
Shiri Freilich grad student
Richard Charles Garratt grad student University of London (Neurotree)
Fabian Gerick grad student
Alex Gutteridge grad student
Abdullah Kahraman grad student
Nicola Kerrison grad student
Hannes Ponstingl grad student
Gareth Stockwell grad student
James Torrance grad student
Gordon Whamond grad student
Matthias Ziehm grad student European Bioinformatics Institute
Carrie M. Wilmot grad student 1989 University of London (Chemistry Tree)
Matthew Bashton post-doc
Sue Jones post-doc
Malcom MacArthur post-doc
Antonio Macchiarulo post-doc (Chemistry Tree)
Tim Massingham post-doc European Bioinformatics Institute
Richard Morris post-doc
Kevin Murray post-doc
Rafael J. Najmanovich post-doc European Bioinformatics Institute (EBI) (Chemistry Tree)
Irilenia Nobeli post-doc
Craig Porter post-doc
Syed  Asad Rahman post-doc European Bioinformatics Institute
Hugh Shanahan post-doc
Ruth Spriggs post-doc
Robert Steward post-doc
John Mitchell post-doc 1991-1998 University College London (Chemistry Tree)
Sarah A. Teichmann post-doc 2000 UCL
Ciaran G. Carolan post-doc 2009-2013 European Molecular Biology Laboratory
Pedro Ballester research scientist European Bioinformatics Institute
Eric Blanc research scientist
Tjaart De Beer research scientist European Bioinformatics Institute
Nicholas Furnham research scientist European Bioinformatics Institute
Fabian Glaser research scientist
Gemma Holliday research scientist European Bioinformatics Institute
Roman Laskowski research scientist European Bioinformatics Institute
Marialuisa Pellegrini-Calace research scientist European Bioinformatics Institute
Gabrielle Reeves research scientist
Eugene Schuster research scientist
David Talavera research scientist
Jon Ward research scientist
James Watson research scientist
Daniela Wieser research scientist European Bioinformatics Institute

Collaborators

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Publications

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Ribeiro AJM, Riziotis IG, Borkakoti N, et al. (2023) Enzyme function and evolution through the lens of bioinformatics. The Biochemical Journal. 480: 1845-1863
Hasenahuer MA, Sanchis-Juan A, Laskowski RA, et al. (2022) Mapping the Constrained Coding Regions in the human genome to their corresponding proteins. Journal of Molecular Biology. 167892
Akdel M, Pires DEV, Pardo EP, et al. (2022) A structural biology community assessment of AlphaFold2 applications. Nature Structural & Molecular Biology
Riziotis IG, Thornton JM. (2022) Capturing the geometry, function, and evolution of enzymes with 3D templates. Protein Science : a Publication of the Protein Society. 31: e4363
Riziotis IG, Ribeiro AJM, Borkakoti N, et al. (2022) Conformational Variation in Enzyme Catalysis: A Structural Study on Catalytic Residues. Journal of Molecular Biology. 434: 167517
Laskowski RA, Thornton JM. (2021) PDBsum extras: SARS-CoV-2 and AlphaFold models. Protein Science : a Publication of the Protein Society
Thornton JM, Laskowski RA, Borkakoti N. (2021) AlphaFold heralds a data-driven revolution in biology and medicine. Nature Medicine. 27: 1666-1669
Magraner-Pardo L, Laskowski RA, Pons T, et al. (2021) A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases. Scientific Reports. 11: 14268
Ochoa R, Laskowski RA, Thornton JM, et al. (2021) Impact of Structural Observables From Simulations to Predict the Effect of Single-Point Mutations in MHC Class II Peptide Binders. Frontiers in Molecular Biosciences. 8: 636562
Ochoa R, Magnitov M, Laskowski RA, et al. (2020) An automated protocol for modelling peptide substrates to proteases. Bmc Bioinformatics. 21: 586
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