Ron Stoop

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Dr. Ron Stoop received his undergraduate training at Nymegen University in the Netherlands in 1987. He subsequently worked for several years in China as scholar and visiting scientist at the Chinese Academy of Sciences and at Tsinghua University before joining Dr. Muming Poo's laboratory at Columbia University for his graduate studies in 1991. He obtained his Ph.D. degree in 1996. After a postdoctoral research training in industry at Glaxo-Welcome Biomedical Research Institute in Geneva (1996-1998) and a first assistant-ship within the Medical Faculty of the University of Lausanne (Department of Cellular Biology and Morphology, 1998-2003), he joined the Centre for Psychiatric Neuroscience as a group leader in 2004.

The Centre for Psychiatric Neuroscience (CNP) has been established in 2002 in a joint effort between the University of Lausanne, the University Hospital of Lausanne (CHUV or Centre Hospitalier Universitaire Vaudois) and the Polytechnical Highschool of Lausanne (EPFL). It accommodates basic neuroscientists with a strong interest in translational neuroscience towards neuropsychiatric diseases. The CNP is situated within the psychiatric hospital community of Cery, located within surroundings of forest and rural landscape at a short distance north of Lausanne. In this unique research setting, neuroscientists and neuropsychiatrists interact on a daily basis to gain deeper understanding into the basic biological mechanisms that may underlie a large range of neuropsychiatric illnesses (see website Cery).

Dr. Stoop's research focuses on the measurement of electrophysiological signaling between hippocampus - amygdala and the output to and interactions of this latter nucleus with the brainstem. To this purpose he uses a newly developed in vitro horizontal slice preparation of the rodent limbic system that includes hippocampus, entorhinal cortex and amygdala and intact connections between these structures (Stoop et al., Eur. J. Neurosci 2000). Measuring methods include extra,- intra,- and whole-cell patch-clamp electrophysiological recording techniques in combination with histological analysis as well as fluorescent imaging and latest molecular biological approaches. Recent findings include the rapid development of persistent epileptiform bursting following short exposures of these slice preparation to the GABA(A) receptor inhibitor bicuculline (Stoop et al., J. Neursci, 2003) and the modulatory effects of oxytocin and vasopressin on the processing of information within the output center of the amygdala (Huber et al., Science, 2005).

(From http://www.bioguider.com/person/neuroscientist/690.html)
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