Anantha Shekhar

Psychiatry Indiana University School of Medicine, Indianapolis, IN, United States 
Schizophrenia, anxiety
"Anantha Shekhar"

Professor Shekhar received his medical degree (M.B., B.S.) in 1981 from St. John's Medical College, Bangalore, India, and his Ph.D. (Medical Neurobiology) from Indiana University in 1993. He completed his residency at Indiana University School of Medicine in 1989 and joined the departments of psychiatry and pharmacology as a faculty member. He was named the Raymond E. Houk chair in Psychiatry in 2003.

He has been the recipient of the prestigious FIRST award from the National Institutes of Mental Health. He has also received a number of honors including the Indiana University Trustees teaching award, outstanding teacher award from the department of psychiatry, and the Nancy Roeske award from the American Psychiatric Association. He has been a tenured member of NIH study section (1999-2005) and has served on many other review committees. He is director of the Indiana Clinical Translational Science Institute.

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Salvadore G, Bonaventure P, Shekhar A, et al. (2020) Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans. Translational Psychiatry. 10: 308
Bernabe CS, Caliman IF, Truitt WA, et al. (2020) Using loss- and gain-of-function approaches to target amygdala-projecting serotonergic neurons in the dorsal raphe nucleus that enhance anxiety-related and conditioned fear behaviors. Journal of Psychopharmacology (Oxford, England). 269881119900981
Patel J, Dustrude E, Haulcomb M, et al. (2020) Role of PSD95 and nNOS Interaction in Gene Regulation following Fear Conditioning and Implications for Molecular Mechanisms Underlying Post-Traumatic Stress Disorder Biological Psychiatry. 87: S334
Niculescu AB, Le-Niculescu H, Roseberry K, et al. (2019) Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs. Molecular Psychiatry
Shekhar A. (2019) Role of Kappa Opioid Receptors in Symptoms of Schizophrenia: What Is the Neurobiology? Biological Psychiatry. 86: 494-496
Donner NC, Mani S, Fitz SD, et al. (2019) Crh receptor priming in the bed nucleus of the stria terminalis induces tph2 gene expression in the dorsomedial dorsal raphe nucleus and chronic anxiety. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 109730
Johnson PL, Molosh AI, Federici LM, et al. (2019) Assessment of fear and anxiety associated behaviors, physiology and neural circuits in rats with reduced serotonin transporter (SERT) levels. Translational Psychiatry. 9: 33
Molosh A, Dustrude E, Lukkes J, et al. (2019) 74. Mechanisms of Agoraphobia: Contribution of Orexin and mGluR2 Signaling in the Amygdala Biological Psychiatry. 85: S30-S31
Dustrude ET, Caliman IF, Bernabe CS, et al. (2018) Orexin Depolarizes Central Amygdala Neurons via Orexin Receptor 1, Phospholipase C and Sodium-Calcium Exchanger and Modulates Conditioned Fear. Frontiers in Neuroscience. 12: 934
Molosh AI, Shekhar A. (2018) Neurofibromatosis type 1 as a model system to study molecular mechanisms of autism spectrum disorder symptoms. Progress in Brain Research. 241: 37-62
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