☰

Alexander Hoffmann

Affiliations: 
Chemistry and Biochemistry University of California, San Diego, La Jolla, CA 
Area:
signaling, transcription, computational network; stress and immune responses, apoptosis, proliferation
Website:
http://www-chem.ucsd.edu/faculty/profiles/hoffmann_alexander.html
Google:
"Alexander Hoffmann"
Mean distance: 8.84
 		SNBCP
Tree Publications Similar researchers PubMed Report error

Parents

Sign in to add mentor
Robert G. Roeder grad student Rockefeller
David Baltimore post-doc Caltech

Children

Sign in to add trainee
Christine S. Huang research assistant 2004-2006 UCSD
Derren Barken grad student 2007 UCSD
Jeffrey D. Kearns grad student 2009 UCSD
Shannon L. Werner grad student 2009 UCSD
Thomas Conrad grad student 2010 UCSD (Computational Biology Tree)
Ellen L. Odea grad student 2010 UCSD
Christine S. Cheng grad student 2011 UCSD
Feng-Sheng Shih grad student 2011 UCSD
Andrew B. Caldwell grad student 2014 UCSD
Karen T. Fortmann grad student 2014 UCSD
Maxim N. Shokhirev grad student 2014 UCSD
Rachel W. Tsui grad student 2014 UCSD
Brooks E. Taylor grad student 2015 UCSD
Simon Mitchell post-doc

Collaborators

Sign in to add collaborator
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Luecke S, Adelaja A, Guo X, et al. (2023) Tonic TNF conditioning of macrophages safeguards stimulus-specific inflammatory responses. Embo Reports. e55986
Mitchell S, Tsui R, Tan ZC, et al. (2023) The NF-κB multidimer system model: A knowledge base to explore diverse biological contexts. Science Signaling. 16: eabo2838
Ando M, Magi S, Seki M, et al. (2021) IκBα is required for full transcriptional induction of some NFκB-regulated genes in response to TNF in MCF-7 cells. Npj Systems Biology and Applications. 7: 42
Son M, Wang AG, Tu HL, et al. (2021) NF-κB responds to absolute differences in cytokine concentrations. Science Signaling. 14
Cheng QJ, Ohta S, Sheu KM, et al. (2021) NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages. Science (New York, N.Y.). 372: 1349-1353
Adelaja A, Taylor B, Sheu KM, et al. (2021) Six distinct NFκB signaling codons convey discrete information to distinguish stimuli and enable appropriate macrophage responses. Immunity. 54: 916-930.e7
Oliver Metzig M, Tang Y, Mitchell S, et al. (2020) An incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions. Molecular Systems Biology. 16: e9677
Lisiero DN, Cheng Z, Tejera MM, et al. (2020) IκBα Nuclear Export Enables 4-1BB-Induced cRel Activation and IL-2 Production to Promote CD8 T Cell Immunity. Journal of Immunology (Baltimore, Md. : 1950)
Ngo KA, Kishimoto K, Davis-Turak J, et al. (2020) Dissecting the Regulatory Strategies of NF-κB RelA Target Genes in the Inflammatory Response Reveals Differential Transactivation Logics. Cell Reports. 30: 2758-2775.e6
Sen S, Cheng Z, Sheu KM, et al. (2020) Gene Regulatory Strategies that Decode the Duration of NFκB Dynamics Contribute to LPS- versus TNF-Specific Gene Expression. Cell Systems
See more...