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Edward H. Koo, MD

Neuroscience University of California, San Diego, La Jolla, CA 
"Edward Koo"
Mean distance: 17.42 (cluster 31)
Cross-listing: Alzheimer's Tree - Neuropathology Tree


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David E. Kang grad student 1995-1999 UCSD
Daniel C. Lu grad student 2001 UCSD
Brea J. Midthune grad student 2012 UCSD
Goonho Park post-doc 2014-
Salvador Soriano post-doc 1997-2001 UCSD
Claus U. Pietrzik post-doc 1998-2003 University of Mainz, Germany
David E. Kang post-doc 1999-2004 UCSD
Sascha Weggen post-doc 1999-2004 UCSD
Markus P. Kummer post-doc 2003-2006 UCSD


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Subhojit Roy collaborator UCSD
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Huang R, Nikooyan AA, Xu B, et al. (2021) Machine learning classifies predictive kinematic features in a mouse model of neurodegeneration. Scientific Reports. 11: 3950
Moore BD, Martin J, de Mena L, et al. (2017) Short Aβ peptides attenuate Aβ42 toxicity in vivo. The Journal of Experimental Medicine
Savas JN, Wang YZ, DeNardo LA, et al. (2017) Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology. Cell Reports. 21: 2614-2627
Eggert S, Gonzalez AC, Thomas C, et al. (2017) Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA. Cellular and Molecular Life Sciences : Cmls
Schilling S, Mehr A, Ludewig S, et al. (2017) APLP1 is a synaptic cell adhesion molecule, supporting maintenance of dendritic spines and basal synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Park SA, Chevallier N, Tejwani K, et al. (2016) Deficiency in either COX-1 or COX-2 genes does not affect amyloid beta protein burden in amyloid precursor protein transgenic mice. Biochemical and Biophysical Research Communications
Lessard CB, Cottrell BA, Maruyama H, et al. (2015) γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP). Plos One. 10: e0144758
Das U, Wang L, Ganguly A, et al. (2015) Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway. Nature Neuroscience
Ling IF, Golde TE, Galasko DR, et al. (2015) Modulation of Aβ42 in vivo by γ-secretase modulator in primates and humans. Alzheimer's Research & Therapy. 7: 55
Jung JI, Price AR, Ladd TB, et al. (2015) Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator. Molecular Neurodegeneration. 10: 29
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