Jeremiah D. Osteen

Affiliations: 
Physiology University of California, San Francisco, San Francisco, CA 
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"Jeremiah Osteen"
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SNBCP

Parents

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Joseph A. Mindell research assistant 2006-2007 NINDS
Robert S. Kass grad student 2007-2012 Columbia
 (Characterization of cardiac I-Ks channel gating using voltage clamp fluorometry.)
David Julius post-doc UCSF
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Publications

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Jones J, Correll DJ, Lechner SM, et al. (2023) Selective Inhibition of Na1.8 with VX-548 for Acute Pain. The New England Journal of Medicine. 389: 393-405
Osteen JD, Sampson K, Iyer V, et al. (2017) Pharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processes. Proceedings of the National Academy of Sciences of the United States of America
Osteen JD, Herzig V, Gilchrist J, et al. (2016) Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature
Barro-Soria R, Osteen JD, Sampson KJ, et al. (2013) Long QT Mutations and KCNE1 β-Subunit Modulate S4 Movement in KCNQ1 Channel Biophysical Journal. 104: 357a
Osteen JD, Barro-Soria R, Robey S, et al. (2012) Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 109: 7103-8
Glaaser IW, Osteen JD, Puckerin A, et al. (2012) Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation. Nature Communications. 3: 706
Chan PJ, Osteen JD, Xiong D, et al. (2012) Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1. The Journal of General Physiology. 139: 135-44
Osteen JD, Robey SH, Barro R, et al. (2012) Allosteric Properties of KCNQ1 (Kv7.1) Channel Gating Detected by Voltage Clamp Fluorometry Biophysical Journal. 102: 332a
Barro-Soria R, Osteen JD, Sampson KJ, et al. (2012) Activation of Voltage Sensing Domains during KCNQ1 Channel Opening: Concerted or Independent? Biophysical Journal. 102: 332a
Wang K, Terrenoire C, Sampson KJ, et al. (2011) Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry. The Journal of Physiology. 589: 6093-104
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