Brian K. Kaspar

Ohio State University Ohio State University, Columbus, Columbus, OH 
Spinal Muscular Atrophy, ALS, CNS Gene Delivery, Gene Therapy
"Brian Kaspar"
Mean distance: 20.46 (cluster 19)
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Powers S, Likhite S, Gadalla KK, et al. (2023) Novel MeCP2 Gene Therapy is Effective in a Multicenter Study using Two Mouse Models of Rett Syndrome and is Safe in Non-human Primates. Molecular Therapy : the Journal of the American Society of Gene Therapy
Johnson TB, Brudvig JJ, Likhite S, et al. (2023) Early postnatal administration of an AAV9 gene therapy is safe and efficacious in CLN3 disease. Frontiers in Genetics. 14: 1118649
Foust KD, Wang X, McGovern VL, et al. (2022) Retraction Note: Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN. Nature Biotechnology
Gomes C, Sequeira C, Likhite S, et al. (2022) Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes. Cells. 11
Liao XH, Avalos P, Shelest O, et al. (2022) AAV9-MCT8 delivery at juvenile stage ameliorates neurological and behavioral deficits in a mouse model of MCT8-deficiency. Thyroid : Official Journal of the American Thyroid Association
Iyer CC, Chugh D, Bobbili PJ, et al. (2021) Follistatin-induced muscle hypertrophy in aged mice improves neuromuscular junction innervation and function. Neurobiology of Aging. 104: 32-41
Chugh D, Iyer CC, Bobbili P, et al. (2021) Voluntary wheel running with and without follistatin overexpression improves NMJ transmission but not motor unit loss in late life of C57BL/6J mice. Neurobiology of Aging
White KA, Nelvagal HR, Poole TA, et al. (2021) Intracranial delivery of AAV9 gene therapy partially prevents retinal degeneration and visual deficits in CLN6-Batten disease mice. Molecular Therapy. Methods & Clinical Development. 20: 497-507
Blatnik AJ, McGovern VL, Le TT, et al. (2020) Conditional deletion of SMN in cell culture identifies functional SMN alleles. Human Molecular Genetics
von Wittgenstein J, Zheng F, Wittmann MT, et al. (2020) Sox11 is an Activity-Regulated Gene with Dentate-Gyrus-Specific Expression Upon General Neural Activation. Cerebral Cortex (New York, N.Y. : 1991)
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