James Shorter

Affiliations: 
Neuroscience University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neuroscience Biology
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"James Shorter"
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Parents

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Graham Warren grad student Yale (Cell Biology Tree)
Susan L. Lindquist post-doc MIT (FlyTree)

Children

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Nathan Todd La Porte research assistant 2009-2010 Penn (Chemistry Tree)
Laura Castellano grad student Penn
Morgan DeSantis grad student Penn
Charlotte M. Fare grad student Penn
Elizabeth Sweeny grad student Penn
Korrie Mack grad student 2013- Penn
Eddie Chuang grad student 2014- Penn
Zach March grad student 2014- Penn
Ryan R. Cupo grad student 2015- Penn
Katie Copley grad student 2019- Penn
Mimi Cushman-Nick grad student 2013 Penn
Alice Ford grad student 2016 Penn
Mike Soo grad student 2016 Penn
Lin Guo post-doc Penn
Meredith E. Jackrel post-doc University of Pennsylvania Medical School (Chemistry Tree)
Mariana Torrente post-doc Penn
JiaBei Lin post-doc 2016- Penn
Edward Barbieri post-doc 2017- Penn
Bede Portz post-doc 2017- Penn
Hana M. Odeh post-doc 2018- Penn
April L. Darling post-doc 2019- Penn (Chemistry Tree)
Erica Gorenberg post-doc 2020- Penn
Shilpa Vashist post-doc 2008-2010 Penn
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Publications

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Shen H, Yanas A, Owens MC, et al. (2022) Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation. Molecular Cell
François-Moutal L, Scott DD, Ambrose AJ, et al. (2022) Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology. Scientific Reports. 12: 8140
Peinado JR, Chaplot K, Jarvela TS, et al. (2022) Sequestration of TDP-43 Aggregates by Cytoplasmic Expression of the proSAAS Chaperone. Acs Chemical Neuroscience
Kim HJ, Mohassel P, Donkervoort S, et al. (2022) Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy. Nature Communications. 13: 2306
Copley KE, Shorter J. (2022) Flying under the radar: TMEM106B(120-254) fibrils break out in diverse neurodegenerative disorders. Cell. 185: 1290-1292
Lin J, Shorter J, Lucius AL. (2022) AAA+ proteins: one motor, multiple ways to work. Biochemical Society Transactions
Ma XR, Prudencio M, Koike Y, et al. (2022) TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A. Nature
Rhine K, Dasovich M, Yoniles J, et al. (2022) Poly(ADP-ribose) drives condensation of FUS via a transient interaction. Molecular Cell
Odeh HM, Shorter J. (2022) Aggregates of TDP-43 protein spiral into view. Nature. 601: 29-30
Gottlieb L, Guo L, Shorter J, et al. (2021) N-alpha-acetylation of Huntingtin protein increases its propensity to aggregate. The Journal of Biological Chemistry. 297: 101363
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