Karen Hedin

Affiliations: 
Neurobiology of Disease College of Medicine - Mayo Clinic 
Area:
Cell Biology, Neuroscience Biology, Immunology
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"Karen Hedin"
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Publications

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Sterner RM, Sakemura R, Yang N, et al. (2019) GM-CSF Blockade during Chimeric Antigen Receptor T-Cell (CART) Therapy Reduces Cytokine Release Syndrome and Neurotoxicity and May Enhance CART Effector Functions Biology of Blood and Marrow Transplantation. 25: S4
Sterner RM, Sakemura R, Cox MJ, et al. (2018) GM-CSF inhibition reduces cytokine release syndrome and neuroinflammation but enhances CAR-T cell function in xenografts. Blood
Dinkel BA, Kremer KN, Rollins MR, et al. (2018) GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation which drives PI3Kγ/PREX1 signaling and T cell cytokine secretion. The Journal of Biological Chemistry
Sterner RM, Kremer KN, Dudakovic A, et al. (2018) Tissue-Nonspecific Alkaline Phosphatase Is Required for MC3T3 Osteoblast-Mediated Protection of Acute Myeloid Leukemia Cells from Apoptosis. Journal of Immunology (Baltimore, Md. : 1950)
Sterner RM, Sakemura R, Yang N, et al. (2018) GM-CSF Blockade during Chimeric Antigen Receptor T Cell Therapy Reduces Cytokine Release Syndrome and Neurotoxicity and May Enhance Their Effector Functions Blood. 132: 961-961
Bowles B, Sterner RM, Kremer KN, et al. (2018) 2559 Role of tissue non-specific alkaline phosphatase (TNAP) in promoting the survival of acute myeloid leukemia (AML) cells within the bone marrow microenvironment Journal of Clinical and Translational Science. 2: 26-27
Kremer KN, Dinkel BA, Sterner RM, et al. (2017) TCR-CXCR4 signaling stabilizes cytokine mRNA transcripts via a PREX1-Rac1 pathway: implications for CTCL. Blood
Sterner R, Kremer K, Dudakovic A, et al. (2016) Abstract 3292: Manipulating osteoblast differentiation in order to inhibit protection of AML cells within the bone marrow Cancer Research. 76: 3292-3292
Kremer KN, Dudakovic A, Hess AD, et al. (2015) Histone deacetylase inhibitors target the leukemic microenvironment by enhancing a Nherf1-Protein Phosphatase 1α-TAZ signaling pathway in osteoblasts. The Journal of Biological Chemistry
Bamidele AO, Kremer KN, Hirsova P, et al. (2015) IQGAP1 promotes CXCR4 chemokine receptor function and trafficking via EEA-1+ endosomes. The Journal of Cell Biology. 210: 257-72
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