Guilian Xu, Ph.D.
Affiliations: | Neuroscience | University of Florida, Gainesville, Gainesville, FL, United States |
Area:
transgenic mice, Alzheimer's disease, ALS,Website:
http://neuroscience.ufl.edu/faculty-and-staff-directory/faculty/guilian-xu-ph-d/Google:
"Guilian Xu"Mean distance: 16.48 (cluster 31) | S | N | B | C | P |
Parents
Sign in to add mentor| STH Chan | grad student | 1996-2001 | The University of Hong Kong |
| Fai Tang | grad student | 1996-2001 | The University of Hong Kong |
| David R. Borchelt | grad student | 1999-2001 | Johns Hopkins |
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Publications
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| De Rossi P, Andrew RJ, Musial TF, et al. (2018) Aberrant accrual of BIN1 near Alzheimer's disease amyloid deposits in transgenic models. Brain Pathology (Zurich, Switzerland) |
| Pace MC, Xu G, Fromholt S, et al. (2018) Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease. Acta Neuropathologica |
| Pace MC, Xu G, Fromholt S, et al. (2018) Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology. Molecular Neurodegeneration. 13: 23 |
| Iradi MCG, Triplett JC, Thomas JD, et al. (2018) Characterization of gene regulation and protein interaction networks for Matrin 3 encoding mutations linked to amyotrophic lateral sclerosis and myopathy. Scientific Reports. 8: 4049 |
| Xu G, Pattamatta A, Hildago R, et al. (2016) Vulnerability of newly synthesized proteins to proteostasis stress. Journal of Cell Science. 129: 1892-901 |
| Xu G, Ran Y, Fromholt SE, et al. (2015) Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits. Acta Neuropathologica Communications. 3: 72 |
| Janus C, Flores AY, Xu G, et al. (2015) Behavioral abnormalities in APPSwe/PS1dE9 mouse model of AD-like pathology: comparative analysis across multiple behavioral domains. Neurobiology of Aging. 36: 2519-32 |
| Li Z, Gu TP, Weber AR, et al. (2015) Gadd45a promotes DNA demethylation through TDG. Nucleic Acids Research. 43: 3986-97 |
| Xu G, Fromholt S, Ayers JI, et al. (2015) Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation. Journal of Neurochemistry. 133: 452-64 |
| Xu G, Ayers JI, Roberts BL, et al. (2015) Direct and indirect mechanisms for wild-type SOD1 to enhance the toxicity of mutant SOD1 in bigenic transgenic mice. Human Molecular Genetics. 24: 1019-35 |