Pamela N. Lopert, Ph.D.

Affiliations: 
2014 Neuroscience University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Neuroscience Biology, Biochemistry
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"Pamela Lopert"
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Parents

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Manisha Patel grad student 2014 University of Colorado, Denver
 (The role of the mitochondrial thioredoxin/thioredoxin reductase antioxidant system in dopaminergic cell death.)
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Publications

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Lopert P, Patel M. (2015) Mitochondrial mechanisms of redox cycling agents implicated in Parkinson's disease. Journal of Neural Transmission (Vienna, Austria : 1996)
Shrotriya S, Deep G, Lopert P, et al. (2014) Grape seed extract targets mitochondrial electron transport chain complex III and induces oxidative and metabolic stress leading to cytoprotective autophagy and apoptotic death in human head and neck cancer cells. Molecular Carcinogenesis
Lopert P, Patel M. (2014) Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption. Redox Biology. 2: 667-72
Lopert P, Patel M. (2014) Nicotinamide nucleotide transhydrogenase (Nnt) links the substrate requirement in brain mitochondria for hydrogen peroxide removal to the thioredoxin/peroxiredoxin (Trx/Prx) system. The Journal of Biological Chemistry. 289: 15611-20
Lopert P, Day BJ, Patel M. (2012) Thioredoxin reductase deficiency potentiates oxidative stress, mitochondrial dysfunction and cell death in dopaminergic cells. Plos One. 7: e50683
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