Weilan Ye

Affiliations: 
Genentech, Inc., San Francisco, CA, United States 
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"Weilan Ye"
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Vitorino P, Yeung S, Crow A, et al. (2015) MAP4K4 regulates integrin-FERM binding to control endothelial cell motility. Nature. 519: 425-30
Wilson CW, Ye W. (2014) Regulation of vascular endothelial junction stability and remodeling through Rap1-Rasip1 signaling. Cell Adhesion & Migration. 8: 76-83
Johnson L, Huseni M, Smyczek T, et al. (2013) Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy. The Journal of Clinical Investigation. 123: 3997-4009
Wilson CW, Parker LH, Hall CJ, et al. (2013) Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood. 122: 3678-90
Sampath D, Oeh J, Wyatt SK, et al. (2013) Multimodal microvascular imaging reveals that selective inhibition of class I PI3K is sufficient to induce an antivascular response. Neoplasia (New York, N.Y.). 15: 694-711
Peale F, Sanders L, Yu R, et al. (2012) Abstract LB-312: Egfl7 is expressed in a broad range of human tumors with apparent restriction to the endothelium Cancer Research. 72
Huseni M, Rosen L, Gordon M, et al. (2011) Abstract 3284: Preclinical and clinical evaluation of pharmacodynamic biomarkers of a novel anti-angiogenesis agent, anti-EGFL7 Cancer Research. 71: 3284-3284
Kadel EE, Huseni M, Kan D, et al. (2010) Abstract 1669: A quantitative real-time RT-PCR gene signature to detect circulating CD34+ cells as a pharmacodynamic biomarker following anti-EGFL7 treatment in preclinical models of efficacy Cancer Research. 70: 1669-1669
Mazière AD, Parker L, Dijk SV, et al. (2008) Egfl7 Knockdown Causes Defects in the Extension and Junctional Arrangements of Endothelial Cells During Zebrafish Vasculogenesis Developmental Dynamics. 237: 580-591
Schmidt M, Mazière AD, Smyczek T, et al. (2007) The role of Egfl7 in vascular morphogenesis. Novartis Foundation Symposium. 283: 18-36
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