Amy E. Ghiretti, Ph.D.

2014 Neuroscience Brandeis University, Waltham, MA, United States 
Neuroscience Biology, Molecular Biology
"Amy Ghiretti"
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Suzanne Paradis grad student 2014 Brandeis
 (Negative regulation of dendritic complexity by the activity-dependent GTPase Rem2.)


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Jeffrey J Nirschl collaborator 2016-2017 Penn (Cell Biology Tree)
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Nirschl JJ, Ghiretti AE, Holzbaur ELF. (2017) The impact of cytoskeletal organization on the local regulation of neuronal transport. Nature Reviews. Neuroscience
Ayloo S, Guedes-Dias P, Ghiretti AE, et al. (2017) Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes. Molecular Biology of the Cell
Ghiretti AE, Thies E, Tokito MK, et al. (2016) Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B. Neuron
Muhia M, Thies E, Labonté D, et al. (2016) The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory. Cell Reports
Nirschl JJ, Ghiretti AE, Holzbaur EL. (2016) Lipid Rafts Assemble Dynein Ensembles. Trends in Biochemical Sciences
Ghiretti AE, Paradis S. (2014) Molecular mechanisms of activity-dependent changes in dendritic morphology: role of RGK proteins. Trends in Neurosciences. 37: 399-407
Ghiretti AE, Moore AR, Brenner RG, et al. (2014) Rem2 is an activity-dependent negative regulator of dendritic complexity in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 392-407
Moore AR, Ghiretti AE, Paradis S. (2013) A loss-of-function analysis reveals that endogenous Rem2 promotes functional glutamatergic synapse formation and restricts dendritic complexity. Plos One. 8: e74751
Ghiretti AE, Kenny K, Marr MT, et al. (2013) CaMKII-dependent phosphorylation of the GTPase Rem2 is required to restrict dendritic complexity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6504-15
Ghiretti AE, Paradis S. (2011) The GTPase Rem2 regulates synapse development and dendritic morphology. Developmental Neurobiology. 71: 374-89
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