Emily Foran, Ph.D.

Affiliations: 
2013 Neuroscience Thomas Jefferson University, Philadelphia, PA, United States 
Area:
Neuroscience Biology
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"Emily Foran"
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Davide Trotti grad student 2013 Thomas Jefferson
 (Implication of a sumoylated c-terminal fragment of the astroglial glutamate transporter, EAAT2 in the non-cell autonomous mechanisms of amyotrophic lateral sclerosis pathogenesis.)
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Publications

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Rosenblum LT, Shamamandri-Markandaiah S, Ghosh B, et al. (2017) Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse model of ALS. Experimental Neurology
Turnquist C, Horikawa I, Foran E, et al. (2016) p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration. Cell Death and Differentiation
Foran E, Kwon DY, Nofziger JH, et al. (2016) CNS uptake of bortezomib is enhanced by P-glycoprotein inhibition: Implications for spinal muscular atrophy. Neurobiology of Disease
Foran E, Rosenblum L, Bogush A, et al. (2014) Sumoylation of the astroglial glutamate transporter EAAT2 governs its intracellular compartmentalization. Glia. 62: 1241-53
Foran E, Rosenblum L, Bogush AI, et al. (2013) Sumoylation of critical proteins in amyotrophic lateral sclerosis: emerging pathways of pathogenesis. Neuromolecular Medicine. 15: 760-70
Foran E, Bogush A, Goffredo M, et al. (2011) Motor neuron impairment mediated by a sumoylated fragment of the glial glutamate transporter EAAT2. Glia. 59: 1719-31
Foran E, Trotti D. (2009) Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis. Antioxidants & Redox Signaling. 11: 1587-602
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