Paul E. Fraser, PhD
Affiliations: | Medical Biophysics | University of Toronto, Toronto, ON, Canada |
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=42Website:
http://neuroscience.utoronto.ca/faculty/list/fraser.htmGoogle:
"Paul Fraser"Mean distance: 106866
Cross-listing: Alzheimer's Tree
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Publications
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Pang KS, Peng HB, Li BP, et al. (2024) Aging and brain free cholesterol concentration on amyloid-β peptide accumulation in guinea pigs. Biopharmaceutics & Drug Disposition |
Eccles MK, Main N, Carlessi R, et al. (2024) Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23396 |
Takamura H, Nakayama Y, Ito H, et al. (2022) SUMO1 Modification of Tau in Progressive Supranuclear Palsy. Molecular Neurobiology. 59: 4419-4435 |
Zhang Y, Zhang Y, Aman Y, et al. (2021) Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway. Brain : a Journal of Neurology |
Joshi P, Riffel F, Satoh K, et al. (2021) Differential interaction with TREM2 modulates microglial uptake of modified Aβ species. Glia |
Ruiz-Riquelme A, Mao A, Barghash MM, et al. (2021) Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice. Acta Neuropathologica Communications. 9: 83 |
Martinez-Valbuena I, Valenti-Azcarate R, Amat-Villegas I, et al. (2021) Mixed pathologies in pancreatic β cells from subjects with neurodegenerative diseases and their interaction with prion protein. Acta Neuropathologica Communications. 9: 64 |
Vilalta A, Zhou Y, Sevalle J, et al. (2021) Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation. The Journal of Biological Chemistry. 100631 |
Wijesekara N, Gonçalves RA, Ahrens R, et al. (2021) Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice. The Journal of Pathology |
Puzzo D, Argyrousi EK, Staniszewski A, et al. (2020) Tau is not necessary for amyloid-beta-induced synaptic and memory impairments. The Journal of Clinical Investigation |