Paul E. Fraser, PhD

Affiliations: 
Medical Biophysics University of Toronto, Toronto, ON, Canada 
Area:
http://www.researchprofiles.collexis.com/jad/expert.asp?u_id=42
Website:
http://neuroscience.utoronto.ca/faculty/list/fraser.htm
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"Paul Fraser"
Mean distance: 106866
 
Cross-listing: Alzheimer's Tree

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Publications

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Pang KS, Peng HB, Li BP, et al. (2024) Aging and brain free cholesterol concentration on amyloid-β peptide accumulation in guinea pigs. Biopharmaceutics & Drug Disposition
Eccles MK, Main N, Carlessi R, et al. (2024) Quantitative comparison of presenilin protein expression reveals greater activity of PS2-γ-secretase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 38: e23396
Takamura H, Nakayama Y, Ito H, et al. (2022) SUMO1 Modification of Tau in Progressive Supranuclear Palsy. Molecular Neurobiology. 59: 4419-4435
Zhang Y, Zhang Y, Aman Y, et al. (2021) Amyloid-β toxicity modulates tau phosphorylation through the PAX6 signalling pathway. Brain : a Journal of Neurology
Joshi P, Riffel F, Satoh K, et al. (2021) Differential interaction with TREM2 modulates microglial uptake of modified Aβ species. Glia
Ruiz-Riquelme A, Mao A, Barghash MM, et al. (2021) Aβ43 aggregates exhibit enhanced prion-like seeding activity in mice. Acta Neuropathologica Communications. 9: 83
Martinez-Valbuena I, Valenti-Azcarate R, Amat-Villegas I, et al. (2021) Mixed pathologies in pancreatic β cells from subjects with neurodegenerative diseases and their interaction with prion protein. Acta Neuropathologica Communications. 9: 64
Vilalta A, Zhou Y, Sevalle J, et al. (2021) Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation. The Journal of Biological Chemistry. 100631
Wijesekara N, Gonçalves RA, Ahrens R, et al. (2021) Combination of human tau and islet amyloid polypeptide exacerbates metabolic dysfunction in transgenic mice. The Journal of Pathology
Puzzo D, Argyrousi EK, Staniszewski A, et al. (2020) Tau is not necessary for amyloid-beta-induced synaptic and memory impairments. The Journal of Clinical Investigation
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