John R. Lukens, Ph.D.

Affiliations: 
2008 University of Virginia, Charlottesville, VA 
Area:
Virology Biology, Immunology
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"John Lukens"

Parents

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Young S. Hahn grad student 2008 UVA
 (Regulation of antiviral CD8+ T-cell responses by HCV.)

Children

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Sushanth Kumar grad student 2017- UVA (Neurotree)
Jessica M. Thanos grad student 2021- UVA
Catherine R. Lammert grad student 2015-2020 UVA
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Publications

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Kumar S, Budhathoki S, Oliveira CB, et al. (2023) Role of the Caspase-8/RIPK3 axis in Alzheimer's disease pathogenesis and Aβ-induced NLRP3 inflammasome activation. Jci Insight
Zengeler KE, Shapiro DA, Bruch KR, et al. (2022) SSRI treatment modifies the effects of maternal inflammation on in utero physiology and offspring neurobiology. Brain, Behavior, and Immunity
Ennerfelt H, Frost EL, Shapiro DA, et al. (2022) SYK coordinates neuroprotective microglial responses in neurodegenerative disease. Cell
Bolte AC, Dutta AB, Hurt ME, et al. (2020) Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis. Nature Communications. 11: 4524
Batista SJ, Still KM, Johanson D, et al. (2020) Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection. Nature Communications. 11: 3687
Ennerfelt HE, Lukens JR. (2020) The role of innate immunity in Alzheimer's disease. Immunological Reviews
Lukens JR, Anand PK. (2020) Adapt(ed) to repair - T2 immune responses in the bladder promote recurrent infections. Nature Immunology
Lammert CR, Frost EL, Bellinger CE, et al. (2020) AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment. Nature. 580: 647-652
Su Z, Frost EL, Lammert CR, et al. (2020) tRNA-derived fragments and microRNAs in the maternal-fetal interface of a mouse maternal-immune-activation autism model. Rna Biology
Kumar S, Lukens JR. (2019) NLRP3 sets the table for a parasitic meal. Journal of Leukocyte Biology
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