Paul C. Spiegel, Ph.D.
Affiliations: | 2004 | University of Washington, Seattle, Seattle, WA |
Area:
Molecular Biology, General Biophysics, Animal Physiology BiologyGoogle:
"Paul Spiegel"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Barry L. Stoddard | grad student | 2004 | University of Washington | |
| (Structural and biochemical studies of blood coagulation factor VIII and LAGLIDADG homing endonucleases.) | ||||
Children
Sign in to add trainee| Bassam G Haddad | research assistant | 2014-2016 | Western Washington University (Neurotree) |
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Childers KC, Avery NG, Estrada Alamo KA, et al. (2023) Structure of coagulation factor VIII bound to a patient-derived anti-C1 domain antibody inhibitor. Blood |
| Childers KC, Peters SC, Spiegel PC. (2022) Structural insights into blood coagulation factor VIII: Procoagulant complexes, membrane binding, and antibody inhibition. Journal of Thrombosis and Haemostasis : Jth |
| Carlson MA, Haddad BG, Weis AJ, et al. (2017) Ribosomal Protein L7/L12 is Required for GTPase Translation Factors EF-G, RF3 and IF2 to Bind in their GTP State to 70S Ribosomes. The Febs Journal |
| Brison CM, Mullen SM, Wuerth ME, et al. (2015) The 1.7 Å X-ray crystal structure of the porcine factor VIII C2 domain and binding analysis to anti-human C2 domain antibodies and phospholipid surfaces. Plos One. 10: e0122447 |
| Shen BW, Spiegel PC, Chang CH, et al. (2008) The tertiary structure and domain organization of coagulation factor VIII. Blood. 111: 1240-7 |
| Spiegel PC, Chevalier B, Sussman D, et al. (2006) The structure of I-CeuI homing endonuclease: Evolving asymmetric DNA recognition from a symmetric protein scaffold. Structure (London, England : 1993). 14: 869-80 |
| Spiegel PC, Kaiser SM, Simon JA, et al. (2004) Disruption of protein-membrane binding and identification of small-molecule inhibitors of coagulation factor VIII. Chemistry & Biology. 11: 1413-22 |
| Spiegel PC, Murphy P, Stoddard BL. (2004) Surface-exposed hemophilic mutations across the factor VIII C2 domain have variable effects on stability and binding activities. The Journal of Biological Chemistry. 279: 53691-8 |
| Bolduc JM, Spiegel PC, Chatterjee P, et al. (2003) Structural and biochemical analyses of DNA and RNA binding by a bifunctional homing endonuclease and group I intron splicing factor. Genes & Development. 17: 2875-88 |
| Spiegel PC, Stoddard BL. (2002) Optimization of factor VIII replacement therapy: can structural studies help in evading antibody inhibitors? British Journal of Haematology. 119: 310-22 |