Klemens Kaupmann

Novartis pharma, Basel, Basel, Basel-Stadt, Switzerland 
GABAB receptors
"Klemens Kaupmann"
Mean distance: 19.33 (cluster 32)
Cross-listing: Chemistry Tree

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Haffke M, Fehlmann D, Rummel G, et al. (2019) Structural basis of species-selective antagonist binding to the succinate receptor. Nature. 574: 581-585
Jacobson LH, Hoyer D, Fehlmann D, et al. (2017) Blunted 5-HT1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABAB1a but not GABAB1b subunit isoforms. Psychopharmacology
Jacobson LH, Sweeney FF, Kaupmann K, et al. (2015) Differential Roles of GABAB1 Subunit Isoforms on Locomotor Responses to Acute and Repeated Administration of Cocaine. Behavioural Brain Research
Krumova P, Reyniers L, Meyer M, et al. (2015) Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 2980-92
Gee CE, Peterlik D, Neuhäuser C, et al. (2014) Blocking metabotropic glutamate receptor subtype 7 (mGlu7) via the Venus flytrap domain (VFTD) inhibits amygdala plasticity, stress, and anxiety-related behavior. The Journal of Biological Chemistry. 289: 10975-87
Baldo B, Weiss A, Parker CN, et al. (2012) A screen for enhancers of clearance identifies huntingtin as a heat shock protein 90 (Hsp90) client protein. The Journal of Biological Chemistry. 287: 1406-14
Herzig MC, Kolly C, Persohn E, et al. (2011) LRRK2 protein levels are determined by kinase function and are crucial for kidney and lung homeostasis in mice. Human Molecular Genetics. 20: 4209-23
Hintermann S, Hurth K, Nozulak J, et al. (2011) Exploring subtype selectivity and metabolic stability of a novel series of ligands for the benzodiazepine binding site of the GABAA receptor. Bioorganic & Medicinal Chemistry Letters. 21: 1523-6
Vlachou S, Paterson NE, Guery S, et al. (2011) Both GABA(B) receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats. European Journal of Pharmacology. 655: 52-8
Maccioni P, Carai MA, Kaupmann K, et al. (2009) Reduction of alcohol's reinforcing and motivational properties by the positive allosteric modulator of the GABA(B) receptor, BHF177, in alcohol-preferring rats. Alcoholism, Clinical and Experimental Research. 33: 1749-56
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