Benjamin F. Cravatt, PhD

Affiliations: 
1997- Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Medicinal Chemistry
Website:
http://www.scripps.edu/research/faculty/cravatt
Google:
"Benjamin Cravatt"
Bio:

Shared the Wolf Prize in Chemistry 2022 "for developing activity-based protein profiling, a chemical proteomic strategy, to characterize enzyme function in native biological systems, and describe numerous enzymes which play critical roles in human biology and disease, including the endocannabinoid hydrolases whose lipid products regulate communication between cells."

Mean distance: 16.87
 
SNBCP
Cross-listing: Chemistry Tree

Parents

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Dale L. Boger grad student 1996 Scripps Institute (Chemistry Tree)
 (Part I. Antibody-catalyzed syn elimination reaction to form a cis olefin. Part II. The Chemistry and biology of 9(Z)-octadecenamide (Oleamide): A sleep-inducing lipid)
Richard A. Lerner grad student 1996 Scripps Institute (Chemistry Tree)

Children

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Xin Jin research assistant 2009-2009 Scripps Institute (Chemistry Tree)
Katy Barglow grad student Scripps Institute (Chemistry Tree)
Jonathan Z. Long grad student The Scripps Research Institute, La Jolla, CA (Cell Biology Tree)
Yujia Wang grad student (Chemistry Tree)
Chu Wang grad student Scripps Institute (Computational Biology Tree)
Matthew P. Patricelli grad student 2001 Scripps Institute
Gregory C. Adam grad student 2003 Scripps Institute
Karen Kustedjo grad student 2003 Scripps Institute
Nadim Jessani grad student 2004 Scripps Institute
Anna E. Speers grad student 2005 Scripps Institute
Michele K. McKinney grad student 2006 Scripps Institute
Gabriel M. Simon grad student 2009 Scripps Institute
Melissa M. Dix grad student 2012 Scripps Institute
Jae W. Chang grad student 2013 Scripps Institute
Armand Bennett Cognetta III grad student 2013-2018 Scripps Institute (Chemistry Tree)
Mikail E Abbasov post-doc Scripps Institute (Chemistry Tree)
Ku-Lung Hsu post-doc (Chemistry Tree)
Siddhesh S. Kamat post-doc Texas A&M University, The Scripps Research Institute (Chemistry Tree)
Heather Murrey post-doc Scripps Institute (Chemistry Tree)
Cleo M. Salisbury post-doc Scripps Institute (Chemistry Tree)
Stephan Sieber post-doc Scripps Institute (Chemistry Tree)
Aaron T. Wright post-doc Scripps Institute (Chemistry Tree)
Megan L. Matthews post-doc 2011- Scripps Institute (Chemistry Tree)
Keriann M. Backus post-doc 2012- (Chemistry Tree)
Christopher G. Parker post-doc 2013- Scripps Institute (Chemistry Tree)
Balyn W. Zaro post-doc 2014- (Chemistry Tree)
Ekaterina Vinogradova post-doc 2015- Scripps Institute (Chemistry Tree)
Xiaoyu Zhang post-doc 2017- Scripps Institute (Chemistry Tree)
Alan Saghatelian post-doc 2002-2006 Scripps Institute (Chemistry Tree)
Erin E. Carlson post-doc 2006-2008 Scripps Institute (Chemistry Tree)
Eranthie Weerapana post-doc 2006-2010 Scripps Institute (Chemistry Tree)
Brent R. Martin post-doc 2007-2010 Scripps Institute (Chemistry Tree)
Daniel K. Nomura post-doc 2008-2011 Scripps Institute (Chemistry Tree)
Raymond E. Moellering post-doc 2011-2014 Scripps Institute (Chemistry Tree)
David B. Konrad post-doc 2018-2019 Scripps Institute (Chemistry Tree)
BETA: Related publications

Publications

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Scott KA, Kojima H, Ropek N, et al. (2023) Covalent Targeting of Splicing in T Cells. Biorxiv : the Preprint Server For Biology
Wichroski M, Benci J, Liu SQ, et al. (2023) DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Science Translational Medicine. 15: eadh1892
Li H, Ma T, Remsberg JR, et al. (2023) Assigning functionality to cysteines by base editing of cancer dependency genes. Nature Chemical Biology
Tao Y, Remillard D, Vinogradova EV, et al. (2023) Correction to "Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1". Journal of the American Chemical Society
Lazear MR, Remsberg JR, Jaeger MG, et al. (2023) Proteomic discovery of chemical probes that perturb protein complexes in human cells. Molecular Cell
Darabedian N, Ji W, Fan M, et al. (2023) Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor. Nature Chemical Biology
Reed A, Ware T, Li H, et al. (2023) TMEM164 is an acyltransferase that forms ferroptotic C20:4 ether phospholipids. Nature Chemical Biology
Kavanagh ME, Horning BD, Khattri R, et al. (2022) Author Correction: Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine. Nature Chemical Biology
Tao Y, Remillard D, Vinogradova EV, et al. (2022) Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1. Journal of the American Chemical Society
Kavanagh ME, Horning BD, Khattri R, et al. (2022) Selective inhibitors of JAK1 targeting an isoform-restricted allosteric cysteine. Nature Chemical Biology
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