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Shun Shimohama, MD, PhD

Neurology Sapporo Medical University, Sapporo-shi, Hokkaidō, Japan 
"Shun Shimohama"

Mean distance: 106866
Cross-listing: Alzheimer's Tree

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Kuroda E, Nishimura K, Kawanishi S, et al. (2020) Mouse Bone Marrow-derived Microglia-like Cells Secrete Transforming Growth Factor-β1 and Promote Microglial Aβ Phagocytosis and Reduction of Brain Aβ. Neuroscience. 438: 217-228
Takata K, Amamiya T, Mizoguchi H, et al. (2017) Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Aβ accumulation through suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis and ameliorates cognitive impairment in a mouse model of Alzheimer's disease. Neurobiology of Aging. 62: 197-209
Watanabe K, Uemura K, Asada M, et al. (2015) The participation of insulin-like growth factor-binding protein 3 released by astrocytes in the pathology of Alzheimer's disease. Molecular Brain. 8: 82
Kato T, Konishi Y, Shimohama S, et al. (2015) Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients. Neuroscience Letters. 591: 19-24
Jingami N, Asada-Utsugi M, Uemura K, et al. (2015) Idiopathic normal pressure hydrocephalus has a different cerebrospinal fluid biomarker profile from Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 45: 109-15
Matsumura A, Suzuki S, Iwahara N, et al. (2015) Temporal changes of CD68 and α7 nicotinic acetylcholine receptor expression in microglia in Alzheimer's disease-like mouse models. Journal of Alzheimer's Disease : Jad. 44: 409-23
Noda Y, Asada M, Kubota M, et al. (2013) Copper enhances APP dimerization and promotes Aβ production. Neuroscience Letters. 547: 10-5
Suzuki S, Kawamata J, Matsushita T, et al. (2013) 3-[(2,4-Dimethoxy)benzylidene]-anabaseine dihydrochloride protects against 6-hydroxydopamine-induced parkinsonian neurodegeneration through α7 nicotinic acetylcholine receptor stimulation in rats. Journal of Neuroscience Research. 91: 462-71
Takata K, Takada T, Ito A, et al. (2012) Microglial Amyloid-β1-40 Phagocytosis Dysfunction Is Caused by High-Mobility Group Box Protein-1: Implications for the Pathological Progression of Alzheimer's Disease. International Journal of Alzheimer's Disease. 2012: 685739
Maesako M, Uemura K, Kubota M, et al. (2012) Environmental enrichment ameliorated high-fat diet-induced Aβ deposition and memory deficit in APP transgenic mice. Neurobiology of Aging. 33: 1011.e11-23
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