Barry D. Greenberg, PhD

Affiliations: 
Neuroscience Drug Discovery and Development at University Health Network, Toronto 
Website:
http://ca.linkedin.com/in/barrydgreenberg
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"Barry Greenberg"
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http://www.google.com/profiles/barry.greenberg1

Mean distance: 106866
 
Cross-listing: Alzheimer's Tree

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Publications

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Greenberg BD, Carrillo MC, Ryan JM, et al. (2013) Improving Alzheimer's disease phase II clinical trials. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 39-49
Shineman DW, Basi GS, Bizon JL, et al. (2011) Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies. Alzheimer's Research & Therapy. 3: 28
Khachaturian ZS, Petersen RC, Snyder PJ, et al. (2011) Developing a global strategy to prevent Alzheimer's disease: Leon Thal Symposium 2010. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 127-32
Khachaturian ZS, Barnes D, Einstein R, et al. (2010) Developing a national strategy to prevent dementia: Leon Thal Symposium 2009. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 89-97
Morissette C, Lacombe D, Kong X, et al. (2007) Potential applications of glycosaminoglycan-related compounds in Alzheimer's disease Pharmacological Mechanisms in Alzheimer's Therapeutics. 255-273
Knappenberger KS, Tian G, Ye X, et al. (2004) Mechanism of gamma-secretase cleavage activation: is gamma-secretase regulated through autoinhibition involving the presenilin-1 exon 9 loop? Biochemistry. 43: 6208-18
Tian G, Ghanekar SV, Aharony D, et al. (2003) The mechanism of gamma-secretase: multiple inhibitor binding sites for transition state analogs and small molecule inhibitors. The Journal of Biological Chemistry. 278: 28968-75
Tian G, Sobotka-Briner CD, Zysk J, et al. (2002) Linear non-competitive inhibition of solubilized human gamma-secretase by pepstatin A methylester, L685458, sulfonamides, and benzodiazepines. The Journal of Biological Chemistry. 277: 31499-505
Zhang J, Ye W, Wang R, et al. (2002) Proteolysis of chimeric beta-amyloid precursor proteins containing the Notch transmembrane domain yields amyloid beta-like peptides. The Journal of Biological Chemistry. 277: 15069-75
Horsburgh K, Cole GM, Yang F, et al. (2000) beta-amyloid (Abeta)42(43), abeta42, abeta40 and apoE immunostaining of plaques in fatal head injury. Neuropathology and Applied Neurobiology. 26: 124-32
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