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Kyle Orwig

Affiliations: 
Microbiology and Molecular Genetics University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology, Cell Biology, Biochemistry
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"Kyle Orwig"
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Bart T. Phillips grad student 2012 University of Pittsburgh
Hanna Valli grad student 2014 University of Pittsburgh

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Publications

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Harancher MR, Sukhwani M, Castro CA, et al. (2023) Generation of two isogenic sickle cell disease induced pluripotent stem cell lines from testicular fibroblasts. Stem Cell Research. 73: 103257
Rajachandran S, Zhang X, Cao Q, et al. (2023) Dissecting the spermatogonial stem cell niche using spatial transcriptomics. Cell Reports. 42: 112737
Munyoki SK, Orwig KE. (2023) Perspectives: Methods for Evaluating Primate Spermatogonial Stem Cells. Methods in Molecular Biology (Clifton, N.J.). 2656: 341-364
Nie X, Munyoki SK, Sukhwani M, et al. (2022) Single-cell analysis of human testis aging and correlation with elevated body mass index. Developmental Cell. 57: 1160-1176.e5
Tran KTD, Valli-Pulaski H, Colvin A, et al. (2022) Male Fertility Preservation and Restoration Strategies for Patients Undergoing Gonadotoxic Therapies. Biology of Reproduction
Tran KTD, Sheng Y, Doungkamchan C, et al. (2022) Induced pluripotent stem cell line from a mouse model of human azoospermia with a frameshift mutation Tex11_1260Ins(TT). Stem Cell Research. 60: 102728
Khampang S, Cho IK, Punyawai K, et al. (2021) Blastocyst development after fertilization with in vitro spermatids derived from nonhuman primate embryonic stem cells. F&S Science. 2: 365-375
Shen YC, Shami AN, Moritz L, et al. (2021) TCF21 mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice. Nature Communications. 12: 3876
Shetty G, Mitchell JM, Lam TNA, et al. (2021) Postpubertal Spermatogonial Stem Cell Transplantation Restores Functional Sperm Production in Rhesus Monkeys Irradiated Before and After Puberty. Andrology
Parker N, Laychur A, Sukwani M, et al. (2021) Spermatogonial Stem Cell Numbers Are Reduced by Transient Inhibition of GDNF Signaling but Restored by Self-Renewing Replication when Signaling Resumes. Stem Cell Reports
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