Michael J. McConnell

Affiliations: 
Biochemistry and Molecular Genetics University of Virginia School of Medicine, Charlottesville, VA, United States 
Area:
somatic mosaicism, neuro-immuno development
Website:
http://www.mcconnell-lab.org
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"Michael McConnell"
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SNBCP

Parents

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Jerold Chun grad student 1999-2004 UCSD
 (An impaired DNA damage response alters neural aneuploidy: Implications for ataxia -telangiectasia.)
Carla J. Shatz post-doc 2004-2008 Harvard Medical School
Fred H. (Rusty) Gage post-doc 2008-2012 Salk Institute
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Publications

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Honrado C, Michel N, Moore JH, et al. (2020) Label-Free Quantification of Cell Cycle Synchronicity of Human Neural Progenitor Cells Based on Electrophysiology Phenotypes. Acs Sensors
Fragola G, Mabb AM, Taylor-Blake B, et al. (2020) Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration. Nature Communications. 11: 1962
Michel N, Majumdar UB, Lannigan J, et al. (2019) Imaging Flow Cytometry Quantifies Neural Genome Dynamics. Cytometry. Part a : the Journal of the International Society For Analytical Cytology
Chronister WD, Burbulis IE, Wierman MB, et al. (2019) Neurons with Complex Karyotypes Are Rare in Aged Human Neocortex. Cell Reports. 26: 825-835.e7
Harbom LJ, Rudisill TL, Michel N, et al. (2018) The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons. Cell and Tissue Research
Harbom LJ, Michel N, McConnell MJ. (2017) Single-cell analysis of diversity in human stem cell-derived neurons. Cell and Tissue Research
Krishnaswami SR, Grindberg RV, Novotny M, et al. (2016) Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons. Nature Protocols. 11: 499-524
Harbom LJ, Chronister WD, McConnell MJ. (2016) Single neuron transcriptome analysis can reveal more than cell type classification: Does it matter if every neuron is unique? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology
Datwani A, McConnell MJ, Kanold PO, et al. (2009) Classical MHCI molecules regulate retinogeniculate refinement and limit ocular dominance plasticity. Neuron. 64: 463-70
McConnell MJ, Huang YH, Datwani A, et al. (2009) H2-K(b) and H2-D(b) regulate cerebellar long-term depression and limit motor learning. Proceedings of the National Academy of Sciences of the United States of America. 106: 6784-9
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