Michael J. McConnell

Affiliations: 
Biochemistry and Molecular Genetics University of Virginia School of Medicine, Charlottesville, VA, United States 
Area:
somatic mosaicism, neuro-immuno development
Website:
http://www.mcconnell-lab.org
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"Michael McConnell"
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SNBCP

Parents

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Jerold Chun grad student 1999-2004 UCSD
 (An impaired DNA damage response alters neural aneuploidy: Implications for ataxia -telangiectasia.)
Carla J. Shatz post-doc 2004-2008 Harvard Medical School
Fred H. (Rusty) Gage post-doc 2008-2012 Salk Institute
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Publications

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Fragola G, Mabb AM, Taylor-Blake B, et al. (2020) Deletion of Topoisomerase 1 in excitatory neurons causes genomic instability and early onset neurodegeneration. Nature Communications. 11: 1962
Michel N, Majumdar UB, Lannigan J, et al. (2019) Imaging Flow Cytometry Quantifies Neural Genome Dynamics. Cytometry. Part a : the Journal of the International Society For Analytical Cytology
Chronister WD, Burbulis IE, Wierman MB, et al. (2019) Neurons with Complex Karyotypes Are Rare in Aged Human Neocortex. Cell Reports. 26: 825-835.e7
Harbom LJ, Rudisill TL, Michel N, et al. (2018) The effect of rho kinase inhibition on morphological and electrophysiological maturity in iPSC-derived neurons. Cell and Tissue Research
Harbom LJ, Michel N, McConnell MJ. (2017) Single-cell analysis of diversity in human stem cell-derived neurons. Cell and Tissue Research
McConnell MJ, Moran JV, Abyzov A, et al. (2017) Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network. Science (New York, N.Y.). 356
Lacar B, Linker SB, Jaeger BN, et al. (2017) Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 8: 15047
Fields FR, Lee SW, McConnell MJ. (2016) Using Bacterial Genomes and Essential Genes for the Development of New Antibiotics. Biochemical Pharmacology
Lacar B, Linker SB, Jaeger BN, et al. (2016) Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 7: 12020
Lacar B, Linker SB, Jaeger BN, et al. (2016) Nuclear RNA-seq of single neurons reveals molecular signatures of activation. Nature Communications. 7: 11022
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