Jeffrey P. Krise

Affiliations: 
Pharmaceutical Chemistry University of Kansas, Lawrence, KS, United States 
Area:
Pharmaceutical Chemistry
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"Jeffrey Krise"
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Publications

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Logan R, Kong AC, Krise JP. (2014) Time-dependent effects of hydrophobic amine-containing drugs on lysosome structure and biogenesis in cultured human fibroblasts. Journal of Pharmaceutical Sciences. 103: 3287-96
Logan R, Kong AC, Axcell E, et al. (2014) Amine-containing molecules and the induction of an expanded lysosomal volume phenotype: a structure-activity relationship study. Journal of Pharmaceutical Sciences. 103: 1572-80
Logan R, Kong A, Krise JP. (2013) Evaluating the roles of autophagy and lysosomal trafficking defects in intracellular distribution-based drug-drug interactions involving lysosomes. Journal of Pharmaceutical Sciences. 102: 4173-80
Ndolo RA, Luan Y, Duan S, et al. (2012) Lysosomotropic properties of weakly basic anticancer agents promote cancer cell selectivity in vitro. Plos One. 7: e49366
Logan R, Funk RS, Axcell E, et al. (2012) Drug-drug interactions involving lysosomes: mechanisms and potential clinical implications. Expert Opinion On Drug Metabolism & Toxicology. 8: 943-58
Funk RS, Krise JP. (2012) Cationic amphiphilic drugs cause a marked expansion of apparent lysosomal volume: implications for an intracellular distribution-based drug interaction. Molecular Pharmaceutics. 9: 1384-95
Ndolo RA, Jacobs DT, Forrest ML, et al. (2010) Intracellular Distribution-based Anticancer Drug Targeting: Exploiting a Lysosomal Acidification Defect Associated with Cancer Cells. Molecular and Cellular Pharmacology. 2: 131-136
Cunningham CW, Mukhopadhyay A, Lushington GH, et al. (2010) Uptake, distribution and diffusivity of reactive fluorophores in cells: implications toward target identification. Molecular Pharmaceutics. 7: 1301-10
Ndolo RA, Forrest ML, Krise JP. (2010) The role of lysosomes in limiting drug toxicity in mice. The Journal of Pharmacology and Experimental Therapeutics. 333: 120-8
Goldman SD, Krise JP. (2010) Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo. The Journal of Biological Chemistry. 285: 4983-94
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