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Gilbert J. Mannering grad student 1958 UW Madison
 (Metabolic N- and O-demethylation of Morphine- and Morphinan-type Analgetics.)
Henry A. Lardy post-doc UW Madison
BETA: Related publications


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Ohkawa S, DiGiacomo B, Larson DL, et al. (1997) 7-Spiroindanyl derivatives of naltrexone and oxymorphone as selective ligands for delta opioid receptors. Journal of Medicinal Chemistry. 40: 1720-5
Rady JJ, Baemmert D, Takemori AE, et al. (1997) Spinal delta opioid receptor subtype activity of 6-monoacetylmorphine in Swiss Webster mice. Pharmacology, Biochemistry, and Behavior. 56: 243-9
Chang AC, Cowan A, Takemori AE, et al. (1996) Aspartic acid conjugates of 2-(3,4-dichlorophenyl)-N-methyl-N-[(1S)-1(3-aminophenyl)-2-(1-pyrrolidi nyl) ethyl]acetamide: kappa opioid receptor agonists with limited access to the central nervous system. Journal of Medicinal Chemistry. 39: 4478-82
Chang AC, Chao CC, Takemori AE, et al. (1996) Arylacetamide-derived fluorescent probes: synthesis, biological evaluation, and direct fluorescent labeling of kappa opioid receptors in mouse microglial cells. Journal of Medicinal Chemistry. 39: 1729-35
Bolognesi ML, Ojala WH, Gleason WB, et al. (1996) Opioid antagonist activity of naltrexone-derived bivalent ligands: importance of a properly oriented molecular scaffold to guide "address" recognition at kappa opioid receptors. Journal of Medicinal Chemistry. 39: 1816-22
Portoghese PS, Farouz-Grant F, Sultana M, et al. (1995) 7'-Substituted amino acid conjugates of naltrindole. Hydrophilic groups as determinants of selective antagonism of delta 1 opioid receptor-mediated antinociception in mice. Journal of Medicinal Chemistry. 38: 402-7
Korlipara VL, Takemori AE, Portoghese PS. (1995) Electrophilic N-benzylnaltrindoles as delta opioid receptor-selective antagonists. Journal of Medicinal Chemistry. 38: 1337-43
Killian P, Holmes BB, Takemori AE, et al. (1995) Cold water swim stress- and delta-2 opioid-induced analgesia are modulated by spinal gamma-aminobutyric acidA receptors. The Journal of Pharmacology and Experimental Therapeutics. 274: 730-4
Chang AC, Takemori AE, Portoghese PS. (1994) 2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-(3-isothiocyanatophenyl)-2-(1-pyrrolidinyl)ethyl]acetamide: an opioid receptor affinity label that produces selective and long-lasting kappa antagonism in mice. Journal of Medicinal Chemistry. 37: 1547-9
Portoghese PS, Lin CE, Farouz-Grant F, et al. (1994) Structure-activity relationship of N17'-substituted norbinaltorphimine congeners. Role of the N17' basic group in the interaction with a putative address subsite on the kappa opioid receptor. Journal of Medicinal Chemistry. 37: 1495-500
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