Robert A. Nichols

University of Hawaii, Honolulu, HI, United States 
Alzheimer's disease
"Robert Nichols"
Mean distance: 13.47 (cluster 11)


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Eric M. Shooter grad student 1977-1982 University of Hawaii
Paul Greengard post-doc 1982-1990
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Arora K, Cheng J, Nichols RA. (2015) Nicotinic Acetylcholine Receptors Sensitize a MAPK-linked Toxicity Pathway on Prolonged Exposure to β-Amyloid. The Journal of Biological Chemistry. 290: 21409-20
Lawrence JL, Tong M, Alfulaij N, et al. (2014) Regulation of presynaptic Ca2+, synaptic plasticity and contextual fear conditioning by a N-terminal β-amyloid fragment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14210-8
Arora K, Alfulaij N, Higa JK, et al. (2013) Impact of sustained exposure to β-amyloid on calcium homeostasis and neuronal integrity in model nerve cell system expressing α4β2 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 288: 11175-90
Pitts MW, Raman AV, Hashimoto AC, et al. (2012) Deletion of selenoprotein P results in impaired function of parvalbumin interneurons and alterations in fear learning and sensorimotor gating. Neuroscience. 208: 58-68
Nichols RA. (2011) Serotonin, presynaptic 5-HT₃ receptors and synaptic plasticity in the developing cerebellum. The Journal of Physiology. 589: 5019-20
Tong M, Arora K, White MM, et al. (2011) Role of key aromatic residues in the ligand-binding domain of alpha7 nicotinic receptors in the agonist action of beta-amyloid. The Journal of Biological Chemistry. 286: 34373-81
Yang K, Buhlman L, Khan GM, et al. (2011) Functional nicotinic acetylcholine receptors containing α6 subunits are on GABAergic neuronal boutons adherent to ventral tegmental area dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2537-48
Khan GM, Tong M, Jhun M, et al. (2010) beta-Amyloid activates presynaptic alpha7 nicotinic acetylcholine receptors reconstituted into a model nerve cell system: involvement of lipid rafts. The European Journal of Neuroscience. 31: 788-96
Dougherty JJ, Nichols RA. (2009) Cross-regulation between colocalized nicotinic acetylcholine and 5-HT3 serotonin receptors on presynaptic nerve terminals. Acta Pharmacologica Sinica. 30: 788-94
Mehta TK, Dougherty JJ, Wu J, et al. (2009) Defining pre-synaptic nicotinic receptors regulated by beta amyloid in mouse cortex and hippocampus with receptor null mutants. Journal of Neurochemistry. 109: 1452-8
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