Robert J. Ferrante, PhD

Neurology, Pathology, & Psychiatry Boston University, Boston, MA, United States 
"Robert Ferrante"

Mean distance: 15.32 (cluster 24)
Cross-listing: Neuropathology Tree

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Tourette C, Farina F, Vazquez-Manrique RP, et al. (2014) The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity. Plos Biology. 12: e1001895
Yano H, Baranov SV, Baranova OV, et al. (2014) Inhibition of mitochondrial protein import by mutant huntingtin. Nature Neuroscience. 17: 822-31
Zhang Y, Cook A, Kim J, et al. (2013) Melatonin inhibits the caspase-1/cytochrome c/caspase-3 cell death pathway, inhibits MT1 receptor loss and delays disease progression in a mouse model of amyotrophic lateral sclerosis. Neurobiology of Disease. 55: 26-35
Taylor DM, Moser R, Régulier E, et al. (2013) MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2313-25
Chopra V, Quinti L, Kim J, et al. (2012) The sirtuin 2 inhibitor AK-7 is neuroprotective in Huntington's disease mouse models. Cell Reports. 2: 1492-7
Landis SC, Amara SG, Asadullah K, et al. (2012) A call for transparent reporting to optimize the predictive value of preclinical research. Nature. 490: 187-91
Zhang Y, Benmohamed R, Zhang W, et al. (2012) Chiral cyclohexane 1,3-diones as inhibitors of mutant SOD1-dependent protein aggregation for the treatment of ALS. Acs Medicinal Chemistry Letters. 3: 584-587
Wright PD, Wightman N, Huang M, et al. (2012) A high-throughput screen to identify inhibitors of SOD1 transcription. Frontiers in Bioscience (Elite Edition). 4: 2801-8
Chen T, Benmohamed R, Kim J, et al. (2012) ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application for the treatment of amyotrophic lateral sclerosis. Journal of Medicinal Chemistry. 55: 515-27
Zhang W, Benmohamed R, Arvanites AC, et al. (2012) Cyclohexane 1,3-diones and their inhibition of mutant SOD1-dependent protein aggregation and toxicity in PC12 cells. Bioorganic & Medicinal Chemistry. 20: 1029-45
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