Smita Saxena, Ph.d
Affiliations: | Institute of Cell Biology, University Bern |
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Publications
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Binda F, Pernaci C, Saxena S. (2020) Cerebellar Development and Circuit Maturation: A Common Framework for Spinocerebellar Ataxias. Frontiers in Neuroscience. 14: 293 |
Hetz C, Saxena S. (2017) ER stress and the unfolded protein response in neurodegeneration. Nature Reviews. Neurology |
Stucki DM, Ruegsegger C, Steiner S, et al. (2016) Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ. Free Radical Biology & Medicine |
Maharjan N, Künzli C, Buthey K, et al. (2016) C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress. Molecular Neurobiology |
Ruegsegger C, Saxena S. (2016) Proteostasis impairment in ALS. Brain Research |
Maharjan N, Saxena S. (2016) ER strikes again: Proteostasis Dysfunction In ALS. The Embo Journal |
Ruegsegger C, Maharjan N, Goswami A, et al. (2015) Aberrant association of misfolded SOD1 with Na(+)/K(+)ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS. Acta Neuropathologica |
Filézac de L'Etang A, Maharjan N, Cordeiro Braña M, et al. (2015) Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS. Nature Neuroscience. 18: 227-38 |
Saxena S, Roselli F, Singh K, et al. (2013) Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. Neuron. 80: 80-96 |
Saxena S, Caroni P. (2011) Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration. Neuron. 71: 35-48 |