Smita Saxena, Ph.d

Affiliations: 
Institute of Cell Biology, University Bern 
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"Smita Saxena"
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Publications

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Binda F, Pernaci C, Saxena S. (2020) Cerebellar Development and Circuit Maturation: A Common Framework for Spinocerebellar Ataxias. Frontiers in Neuroscience. 14: 293
Hetz C, Saxena S. (2017) ER stress and the unfolded protein response in neurodegeneration. Nature Reviews. Neurology
Stucki DM, Ruegsegger C, Steiner S, et al. (2016) Mitochondrial impairments contribute to Spinocerebellar ataxia type 1 progression and can be ameliorated by the mitochondria-targeted antioxidant MitoQ. Free Radical Biology & Medicine
Maharjan N, Künzli C, Buthey K, et al. (2016) C9ORF72 Regulates Stress Granule Formation and Its Deficiency Impairs Stress Granule Assembly, Hypersensitizing Cells to Stress. Molecular Neurobiology
Ruegsegger C, Saxena S. (2016) Proteostasis impairment in ALS. Brain Research
Maharjan N, Saxena S. (2016) ER strikes again: Proteostasis Dysfunction In ALS. The Embo Journal
Ruegsegger C, Maharjan N, Goswami A, et al. (2015) Aberrant association of misfolded SOD1 with Na(+)/K(+)ATPase-α3 impairs its activity and contributes to motor neuron vulnerability in ALS. Acta Neuropathologica
Filézac de L'Etang A, Maharjan N, Cordeiro Braña M, et al. (2015) Marinesco-Sjögren syndrome protein SIL1 regulates motor neuron subtype-selective ER stress in ALS. Nature Neuroscience. 18: 227-38
Saxena S, Roselli F, Singh K, et al. (2013) Neuroprotection through excitability and mTOR required in ALS motoneurons to delay disease and extend survival. Neuron. 80: 80-96
Saxena S, Caroni P. (2011) Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration. Neuron. 71: 35-48
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