Noah Gregory Shuart
Affiliations: | University of Washington, Seattle, Seattle, WA |
Area:
CryoEM, membrane proteinsGoogle:
"Noah Shuart"Mean distance: 15.48 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Tamir Gonen | grad student | University of Washington | ||
| William N. Zagotta | grad student | 2009 | University of Washington | |
| (Role of C-terminal region in heteromeric assembly of cyclic nucleotide-gated channels.) | ||||
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Publications
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| Focken T, Burford K, Grimwood ME, et al. (2019) Identification of CNS-Penetrant Aryl Sulfonamides as Isoform-Selective NaV1.6 Inhibitors with Efficacy in Mouse Models of Epilepsy. Journal of Medicinal Chemistry |
| Bankar G, Goodchild SJ, Howard S, et al. (2018) Selective Na1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain. Cell Reports. 24: 3133-3145 |
| Ghovanloo MR, Shuart NG, Mezeyova J, et al. (2018) Inhibitory effects of cannabidiol on voltage-dependent sodium currents. The Journal of Biological Chemistry |
| Focken T, Chowdhury S, Zenova A, et al. (2018) Design of Conformationally Constrained Acyl Sulfonamide Isosteres: Identification of N-([1,2,4]Triazolo[4,3-a]pyridin-3-yl)methane-sulfonamides as Potent and Selective hNaV1.7 Inhibitors for the Treatment of Pain. Journal of Medicinal Chemistry |
| Focken T, Liu S, Chahal N, et al. (2016) Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models. Acs Medicinal Chemistry Letters. 7: 277-82 |
| Shuart NG, Haitin Y, Camp SS, et al. (2011) Molecular mechanism for 3:1 subunit stoichiometry of rod cyclic nucleotide-gated ion channels. Nature Communications. 2: 457 |
| Budzinski KL, Sgro AE, Fujimoto BS, et al. (2011) Synaptosomes as a platform for loading nanoparticles into synaptic vesicles. Acs Chemical Neuroscience. 2: 236-241 |