Jean-Charles Schwartz, Ph.D
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"Jean-Charles Schwartz"Mean distance: 16.65 (cluster 11)
Children
Sign in to add trainee| Jean Costentin | grad student | ||
| Elisabeth Traiffort | grad student | ||
| Bruno Giros | grad student | 1983-1987 | INSERM, Paris |
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Publications
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| Rusjan PM, Sabioni P, Di Ciano P, et al. (2020) Exploring Occupancy of the Histamine H3 Receptor by Pitolisant in Humans Using Positron Emission Tomography. British Journal of Pharmacology |
| Lecendreux M, Plazzi G, Franco P, et al. (2019) Pharmacokinetics of pitolisant in children and adolescents with narcolepsy. Sleep Medicine. 66: 220-226 |
| Setnik B, McDonnell M, Mills C, et al. (2019) Evaluation of the abuse potential of pitolisant, a selective H3-receptor antagonist/inverse agonist, for the treatment of adult patients with narcolepsy with or without cataplexy. Sleep |
| Dauvilliers Y, Arnulf I, Szakacs Z, et al. (2019) Long-term use of pitolisant to treat patients with narcolepsy: Harmony III Study. Sleep |
| Thorpy M, Schwartz J, Lecomte J, et al. (2018) 0624 Anticataplectic Efficacy of Pitolisant, the First Potent and Highly Selective Histamine H3-Receptor Antagonist/Inverse Agonist Sleep. 41 |
| Szakacs Z, Dauvilliers Y, Mikhaylov V, et al. (2017) Safety and efficacy of pitolisant on cataplexy in patients with narcolepsy: a randomised, double-blind, placebo-controlled trial. The Lancet. Neurology |
| Levoin N, Labeeuw O, Billot X, et al. (2016) Discovery of nanomolar ligands with novel scaffolds for the histamine H4 receptor by virtual screening. European Journal of Medicinal Chemistry. 125: 565-572 |
| Labeeuw O, Levoin N, Billot X, et al. (2016) Synthesis and evaluation of a 2-benzothiazolylphenylmethyl ether class of histamine H4 receptor antagonists. Bioorganic & Medicinal Chemistry Letters |
| Schwartz JC, Lecomte JM. (2016) Clinical trials with H3-receptor inverse agonists: what they tell us about the role of histamine in the human brain. Neuropharmacology |
| Capet M, Calmels T, Levoin N, et al. (2015) Improving selectivity of dopamine D3 receptor ligands. Bioorganic & Medicinal Chemistry Letters |