Manuel Covarrubias

Affiliations: 
Thomas Jefferson University, Philadelphia, PA, United States 
Area:
K channels
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"Manuel Covarrubias"
Mean distance: 23190.8
 
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Publications

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Liang Q, Chi G, Cirqueira L, et al. (2024) The binding and mechanism of a positive allosteric modulator of Kv3 channels. Nature Communications. 15: 2533
Feng H, Clatot J, Kaneko K, et al. (2024) Targeted therapy improves cellular dysfunction, ataxia, and seizure susceptibility in a model of a progressive myoclonus epilepsy. Cell Reports. Medicine. 101389
Clatot J, Currin CB, Liang Q, et al. (2024) A structurally precise mechanism links an epilepsy-associated potassium channel mutation to interneuron dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 121: e2307776121
Alexander TD, Muqeem T, Zhi L, et al. (2022) Tunable Action Potential Repolarization Governed by Kv3.4 Channels in Dorsal Root Ganglion Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Chi G, Liang Q, Sridhar A, et al. (2022) Cryo-EM structure of the human Kv3.1 channel reveals gating control by the cytoplasmic T1 domain. Nature Communications. 13: 4087
Yang E, Bu W, Suma A, et al. (2021) Binding Sites and the Mechanism of Action of Propofol and a Photoreactive Analogue in Prokaryotic Voltage-Gated Sodium Channels. Acs Chemical Neuroscience. 12: 3898-3914
Ojala KS, Ginebaugh SP, Wu M, et al. (2021) A high affinity, partial antagonist effect of 3,4-diaminopyridine mediates action potential broadening and enhancement of transmitter release at NMJs. The Journal of Biological Chemistry. 100302
Zemel BM, Zhi L, Brown EV, et al. (2021) PKCε associates with the Kv3.4 channel to promote its expression in a kinase activity-dependent manner. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21241
Zemel BM, Ritter DM, Covarrubias M, et al. (2018) A-Type K Channels in Dorsal Root Ganglion Neurons: Diversity, Function, and Dysfunction. Frontiers in Molecular Neuroscience. 11: 253
Wang Y, Yang E, Wells MM, et al. (2018) Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites. The Journal of General Physiology
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