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Peter Brazda, Ph.D.

2019- Princess Máxima Center for Pediatric Oncology 
molecular biology, cancer biology, single cell transcriptomics, single molecule biophysics
"Peter Brazda"
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Joerg Langowski collaborator 2008-2015 German Cancer Research Center (DKFZ) (Computational Biology Tree)
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Rehó B, Lau L, Mocsár G, et al. (2019) Simultaneous mapping of molecular proximity and co-mobility reveals agonist-enhanced dimerization and DNA binding of nuclear receptors. Analytical Chemistry
Smith DG, Martinelli R, Besra GS, et al. (2019) Identification and characterization of a novel anti-inflammatory lipid isolated from Mycobacterium vaccae, a soil-derived bacterium with immunoregulatory and stress resilience properties. Psychopharmacology
de Leeuw R, Brazda P, Charl Moolman M, et al. (2017) Measuring In Vivo Protein Dynamics Throughout the Cell Cycle Using Microfluidics. Methods in Molecular Biology (Clifton, N.J.). 1624: 237-252
Brazda P, Krieger J, Daniel B, et al. (2014) Ligand binding shifts highly mobile retinoid X receptor to the chromatin-bound state in a coactivator-dependent manner, as revealed by single-cell imaging. Molecular and Cellular Biology. 34: 1234-45
Krieger JW, Pernus A, Brazda P, et al. (2014) Protein interaction and transport maps of live cell nuclei using fluorescence correlation spectroscopy in a single plane illumination microscope Microscopy and Microanalysis. 20: 1196-1197
Brazda P, Szekeres T, Bravics B, et al. (2011) Live-cell fluorescence correlation spectroscopy dissects the role of coregulator exchange and chromatin binding in retinoic acid receptor mobility. Journal of Cell Science. 124: 3631-42
Tóth K, Sarang Z, Scholtz B, et al. (2011) Retinoids enhance glucocorticoid-induced apoptosis of T cells by facilitating glucocorticoid receptor-mediated transcription. Cell Death and Differentiation. 18: 783-92
Vámosi G, Baudendistel N, von der Lieth CW, et al. (2008) Conformation of the c-Fos/c-Jun complex in vivo: a combined FRET, FCCS, and MD-modeling study. Biophysical Journal. 94: 2859-68
Szatmari I, Vámosi G, Brazda P, et al. (2006) Peroxisome proliferator-activated receptor gamma-regulated ABCG2 expression confers cytoprotection to human dendritic cells. The Journal of Biological Chemistry. 281: 23812-23
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