Liam P. Tuffy

Max-Planck-Institute for Experimental Medicine, Göttingen, Germany 
Synaptic adhesion mechanisms, neurodegeneration
"Liam Tuffy"
Mean distance: 15.28 (cluster 11)
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Ripamonti S, Ambrozkiewicz MC, Guzzi F, et al. (2017) Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. Elife. 6
Hammer M, Krueger-Burg D, Tuffy LP, et al. (2015) Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism. Cell Reports. 13: 516-23
Poulopoulos A, Soykan T, Tuffy LP, et al. (2012) Homodimerization and isoform-specific heterodimerization of neuroligins. The Biochemical Journal. 446: 321-30
Krueger DD, Tuffy LP, Papadopoulos T, et al. (2012) The role of neurexins and neuroligins in the formation, maturation, and function of vertebrate synapses. Current Opinion in Neurobiology. 22: 412-22
D'Orsi B, Bonner H, Tuffy LP, et al. (2012) Calpains are downstream effectors of bax-dependent excitotoxic apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1847-58
Weisová P, Dávila D, Tuffy LP, et al. (2011) Role of 5'-adenosine monophosphate-activated protein kinase in cell survival and death responses in neurons. Antioxidants & Redox Signaling. 14: 1863-76
Flanagan L, Sebastià J, Tuffy LP, et al. (2010) XIAP impairs Smac release from the mitochondria during apoptosis. Cell Death & Disease. 1: e49
Tuffy LP, Concannon CG, D'Orsi B, et al. (2010) Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition. Molecular and Cellular Biology. 30: 5484-501
Concannon CG, Tuffy LP, Weisová P, et al. (2010) AMP kinase-mediated activation of the BH3-only protein Bim couples energy depletion to stress-induced apoptosis. The Journal of Cell Biology. 189: 83-94
Murphy BM, Engel T, Paucard A, et al. (2010) Contrasting patterns of Bim induction and neuroprotection in Bim-deficient mice between hippocampus and neocortex after status epilepticus. Cell Death and Differentiation. 17: 459-68
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