Timothy B. Johnstone, Ph.D.
Affiliations: | 2002 | University of California, Irvine, Irvine, CA |
Area:
PharmacologyGoogle:
"Timothy Johnstone"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Kelvin W. Gee | grad student | 2002 | UC Irvine | |
| (Elucidation of a putative novel allosteric modulatory site on the GABA(A) receptor complex.) | ||||
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Publications
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| Sangadi DK, Sangadi A, Placeres-Uray F, et al. (2023) Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation. Experimental Neurology. 372: 114647 |
| Titus DJ, Johnstone T, Johnson NH, et al. (2019) Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury. Plos One. 14: e0223180 |
| Reddy DS, Yoshimura RF, Ramanathan G, et al. (2018) Role of β-specific GABA-A receptor isoforms in the development of hippocampus kindling epileptogenesis. Epilepsy & Behavior : E&B. 82: 57-63 |
| Yoshimura RF, Tran MB, Hogenkamp DJ, et al. (2017) Allosteric modulation of nicotinic and GABAA receptor subtypes differentially modify autism-like behaviors in the BTBR mouse model. Neuropharmacology |
| Gee KW, Olincy A, Kanner R, et al. (2017) First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288. Journal of Psychopharmacology (Oxford, England). 269881117691590 |
| Dasse O, Bilcer G, Putman D, et al. (2015) APN0417: A potent and efficacious α7 nAChR positive allosteric modulator Biochemical Pharmacology. 97: 636 |
| Titus DJ, Concepcion F, Johnstone T, et al. (2015) Positive allosteric modulation of the α7 nicotinic acetylcholine receptor reverses chronic cognitive deficits after TBI Biochemical Pharmacology. 97: 635 |
| Hogenkamp DJ, Tran MB, Yoshimura RF, et al. (2014) Pharmacological profile of a 17β-heteroaryl-substituted neuroactive steroid. Psychopharmacology. 231: 3517-24 |
| Yoshimura RF, Tran MB, Hogenkamp DJ, et al. (2014) Limited central side effects of a β-subunit subtype-selective GABAA receptor allosteric modulator. Journal of Psychopharmacology (Oxford, England). 28: 472-8 |
| Hogenkamp DJ, Ford-Hutchinson TA, Li WY, et al. (2013) Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of α7 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 56: 8352-65 |