Ryan F. Yoshimura, Ph.D.
Affiliations: | 2008 | University of California, Irvine, Irvine, CA |
Area:
PharmacologyGoogle:
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Parents
Sign in to add mentor| Kelvin W. Gee | grad student | 2008 | UC Irvine | |
| (Therapeutic potential for negative allosteric modulators of nicotinic acetylcholine receptors.) | ||||
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Publications
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| Reddy DS, Yoshimura RF, Ramanathan G, et al. (2018) Role of β-specific GABA-A receptor isoforms in the development of hippocampus kindling epileptogenesis. Epilepsy & Behavior : E&B. 82: 57-63 |
| Yoshimura RF, Tran MB, Hogenkamp DJ, et al. (2017) Allosteric modulation of nicotinic and GABAA receptor subtypes differentially modify autism-like behaviors in the BTBR mouse model. Neuropharmacology |
| Gee KW, Olincy A, Kanner R, et al. (2017) First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288. Journal of Psychopharmacology (Oxford, England). 269881117691590 |
| Dasse O, Bilcer G, Putman D, et al. (2015) APN0417: A potent and efficacious α7 nAChR positive allosteric modulator Biochemical Pharmacology. 97: 636 |
| Koelsch G, Detke MJ, Stevens KE, et al. (2015) APN1125: A clinical stage α7 nicotinic acetylcholine receptor partial agonist Biochemical Pharmacology. 97: 636 |
| Hogenkamp DJ, Tran MB, Yoshimura RF, et al. (2014) Pharmacological profile of a 17β-heteroaryl-substituted neuroactive steroid. Psychopharmacology. 231: 3517-24 |
| Yoshimura RF, Tran MB, Hogenkamp DJ, et al. (2014) Limited central side effects of a β-subunit subtype-selective GABAA receptor allosteric modulator. Journal of Psychopharmacology (Oxford, England). 28: 472-8 |
| Koelsch G, Meltzer LT, Yoshimura RF, et al. (2014) P4-373: APN1125: A NOVEL A7 NICOTINIC ACETYLCHOLINE RECEPTOR PARTIAL AGONIST Alzheimer's & Dementia. 10: P925-P925 |
| Hogenkamp DJ, Ford-Hutchinson TA, Li WY, et al. (2013) Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of α7 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 56: 8352-65 |
| Johnstone TB, Gu Z, Yoshimura RF, et al. (2011) Allosteric modulation of related ligand-gated ion channels synergistically induces long-term potentiation in the hippocampus and enhances cognition. The Journal of Pharmacology and Experimental Therapeutics. 336: 908-15 |