David C. Klein

Affiliations: 
National Institute of Child Health and Human Development, Bethesda, MD, United States 
Area:
Melatonin Biosynthesis
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"David Klein"
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Mark J. Zylka research assistant 1991-1994 NICHD
Steven M. Reppert post-doc NICHD
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Publications

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Carstensen MB, Hertz H, Bering T, et al. (2019) Circadian regulation and molecular role of the Bsx homeobox gene in the adult pineal gland. Journal of Pineal Research. e12629
Hertz H, Carstensen MB, Bering T, et al. (2019) The Lhx4 homeobox transcript in the rat pineal gland: adrenergic regulation and impact on transcripts encoding melatonin-synthesizing enzymes. Journal of Pineal Research. e12616
Mays JC, Kelly MC, Coon SL, et al. (2018) Single-cell RNA sequencing of the mammalian pineal gland identifies two pinealocyte subtypes and cell type-specific daily patterns of gene expression. Plos One. 13: e0205883
Backlund PS, Urbanski HF, Doll MA, et al. (2017) Daily Rhythm in Plasma N-acetyltryptamine. Journal of Biological Rhythms. 748730417700458
Ben-Moshe Livne Z, Alon S, Vallone D, et al. (2016) Genetically Blocking the Zebrafish Pineal Clock Affects Circadian Behavior. Plos Genetics. 12: e1006445
Hartley SW, Mullikin JC, Klein DC, et al. (2016) Alternative Isoform Analysis of Ttc8 Expression in the Rat Pineal Gland Using a Multi-Platform Sequencing Approach Reveals Neural Regulation. Plos One. 11: e0163590
Rath MF, Coon SL, Amaral FG, et al. (2016) Melatonin synthesis: Acetylserotonin O-methyltransferase (ASMT) is strongly expressed in a subpopulation of pinealocytes in the male rat pineal gland. Endocrinology. en20151888
Hartley SW, Coon SL, Savastano LE, et al. (2015) Neurotranscriptomics: The Effects of Neonatal Stimulus Deprivation on the Rat Pineal Transcriptome. Plos One. 10: e0137548
Yamazaki F, Møller M, Fu C, et al. (2015) The Lhx9 homeobox gene controls pineal gland development and prevents postnatal hydrocephalus. Brain Structure & Function. 220: 1497-509
Falcón J, Coon SL, Besseau L, et al. (2014) Drastic neofunctionalization associated with evolution of the timezyme AANAT 500 Mya. Proceedings of the National Academy of Sciences of the United States of America. 111: 314-9
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