Malcolm J. Low, M.D., Ph.D

Affiliations: 
Oregon Health and Science University, Portland, OR 
 Molecular & Integrative Physiology and Metabolism, Endocrinology & Diabetes University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
obesity, diabetes, hypothalamus
Website:
https://www.umms.med.umich.edu/pibsfacsearch/facultyPage.do?facUniqname=mjlow
Google:
"Malcolm Low"
Mean distance: 15.74 (cluster 52)
 
SNBCP
Cross-listing: Chemistry Tree

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Publications

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Zhou Y, Leri F, Low MJ, et al. (2019) Sex differences in the effect of bupropion and naltrexone combination on alcohol drinking in mice. Pharmacology, Biochemistry, and Behavior
Jones GL, Wittmann G, Yokosawa EB, et al. (2019) Selective Restoration of Expression in Glutamatergic POMC Neurons: Evidence for a Dynamic Hypothalamic Neurotransmitter Network. Eneuro. 6
Orquera DP, Tavella MB, de Souza FSJ, et al. (2019) The homeodomain transcription factor NKX2.1 is essential for the early specification of melanocortin neuron identity and activates expression in the developing hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Tooke BP, Yu H, Adams JM, et al. (2018) Hypothalamic POMC or MC4R deficiency impairs counterregulatory responses to hypoglycemia in mice. Molecular Metabolism
Kim GH, Shi G, Somlo DR, et al. (2018) Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity. The Journal of Clinical Investigation
Steyn FJ, Ngo ST, Chen VP, et al. (2017) 17α-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior. Aging Cell
Zhou Y, Rubinstein M, Low M, et al. (2017) V1b receptor antagonist SSR149415 and naltrexone synergistically decrease excessive alcohol drinking in male and female mice. Alcoholism, Clinical and Experimental Research
Chhabra KH, Morgan DA, Tooke BP, et al. (2017) Reduced renal sympathetic nerve activity contributes to elevated glycosuria and improved glucose tolerance in hypothalamus-specific Pomc knockout mice. Molecular Metabolism. 6: 1274-1285
Burke LK, Ogunnowo-Bada E, Georgescu T, et al. (2017) Lorcaserin improves glycemic control via a melanocortin neurocircuit. Molecular Metabolism. 6: 1092-1102
Rubinstein M, Low MJ. (2017) Molecular and functional genetics of the proopiomelanocortin gene, food intake regulation and obesity. Febs Letters
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