James L. Manley, Ph. D.
Affiliations: | Biological Sciences | Columbia University, New York, NY |
Area:
mRNA processingWebsite:
http://www.columbia.edu/cu/biology/faculty/manley/Google:
"James L. Manley"Bio:
http://www.nasonline.org/member-directory/members/20024806.html
https://www.elifesciences.org/about/elife-community/editorial-leadership/james-manley-senior-editor/
http://www.columbia.edu/cu/biology/faculty/manley/Manley%20CV%20.pdf
Mean distance: 16.59 (cluster 11) | S | N | B | C | P |
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| Geoffrey Louis Zubay | research assistant | 1970-1972 | Columbia (Chemistry Tree) | |
| Raymond F. Gesteland | grad student | 1972-1976 | SUNY Stony Brook (Chemistry Tree) | |
| (Properties of in vivo and in vitro synthesized abnormal polypeptides encoded by the lacZ gene of E. coli) | ||||
| Malcolm L. Gefter | post-doc | 1977-1980 | MIT (Chemistry Tree) | |
Children
Sign in to add trainee| Xin-Yuan Fu | grad student | 1988 | Columbia |
| Baohe Shen | grad student | 2000 | Columbia |
| Moonkyoung Um | grad student | 2000 | Columbia |
| Zheng Chen | grad student | 2003 | Columbia |
| Saba Valadkhan | grad student | 2003 | Columbia |
| Chanseok Shin | grad student | 2004 | Columbia |
| Shuzo Kaneko | grad student | 2007 | Columbia |
| Adelene Y. Tan | grad student | 2010 | Columbia |
| Dafne Campigli Di Giammartino | grad student | 2014 | Columbia |
| Kevin Ryan | post-doc | 1999-2003 | Columbia (Chemistry Tree) |
| Frida E. Kleiman | post-doc | 2004 | Columbia (Chemistry Tree) |
BETA: Related publications
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Publications
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| Feng S, Desotell A, Ross A, et al. (2023) A nucleolar long "non-coding" RNA encodes a novel protein that functions in response to stress. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221109120 |
| Zhang J, Huang J, Xu K, et al. (2022) DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer. Proceedings of the National Academy of Sciences of the United States of America. 119: e2216712119 |
| Feng S, Manley JL. (2022) Beyond rRNA: nucleolar transcription generates a complex network of RNAs with multiple roles in maintaining cellular homeostasis. Genes & Development. 36: 876-886 |
| Tsai YL, Mu YC, Manley JL. (2022) Nuclear RNA transcript levels modulate nucleocytoplasmic distribution of ALS/FTD-associated protein FUS. Scientific Reports. 12: 8180 |
| Yamazaki T, Liu L, Manley JL. (2021) Oxidative stress induces Ser 2 dephosphorylation of the RNA polymerase II CTD and premature transcription termination. Transcription. 1-17 |
| Feng S, Manley JL. (2021) Replication protein A associates with nucleolar R loops and regulates rRNA transcription and nucleolar morphology. Genes & Development |
| Wang Q, Conlon E, Manley J, et al. (2020) Widespread intron retention impairs protein homeostasis in C9orf72 ALS brains. Genome Research |
| Richard P, Feng S, Tsai YL, et al. (2020) SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. Autophagy |
| Cheng LC, Zheng D, Baljinnyam E, et al. (2020) Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation. Nature Communications. 11: 3182 |
| Yamazaki T, Liu L, Colon EG, et al. (2020) Burkitt-lymphoma-related mutations alter TCF3 alternative splicing by disrupting hnRNPH1 binding. Rna Biology |