Ji Chu, Ph.D.
Affiliations: | 2009 | Pharmacology | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
Cell Biology, Pharmacology, Molecular BiologyGoogle:
"Ji Chu"Mean distance: 35622
Parents
Sign in to add mentor| Ping-Yee Law | grad student | 2009 | UMN | |
| (Agonist-dependent mechanism of mu-opioid receptor desensitization.) | ||||
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Publications
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| Zheng H, Pearsall EA, Hurst DP, et al. (2012) Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling. Bmc Cell Biology. 13: 6 |
| Zheng H, Zou H, Liu X, et al. (2012) Cholesterol level influences opioid signaling in cell models and analgesia in mice and humans. Journal of Lipid Research. 53: 1153-62 |
| Zheng H, Chu J, Zhang Y, et al. (2011) Modulating micro-opioid receptor phosphorylation switches agonist-dependent signaling as reflected in PKCepsilon activation and dendritic spine stability. The Journal of Biological Chemistry. 286: 12724-33 |
| Zheng H, Zeng Y, Chu J, et al. (2010) Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl on dendritic spine stability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8102-10 |
| Zheng H, Chu J, Zeng Y, et al. (2010) Yin Yang 1 phosphorylation contributes to the differential effects of mu-opioid receptor agonists on microRNA-190 expression. The Journal of Biological Chemistry. 285: 21994-2002 |
| Chu J, Zheng H, Zhang Y, et al. (2010) Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization. Cellular Signalling. 22: 684-96 |
| Zheng H, Zeng Y, Zhang X, et al. (2010) mu-Opioid receptor agonists differentially regulate the expression of miR-190 and NeuroD. Molecular Pharmacology. 77: 102-9 |
| Zheng H, Chu J, Qiu Y, et al. (2008) Agonist-selective signaling is determined by the receptor location within the membrane domains. Proceedings of the National Academy of Sciences of the United States of America. 105: 9421-6 |
| Chu J, Zheng H, Loh HH, et al. (2008) Morphine-induced mu-opioid receptor rapid desensitization is independent of receptor phosphorylation and beta-arrestins. Cellular Signalling. 20: 1616-24 |
| Chu J, Loh HH, Law P. (2007) Agonist‐direct Mu‐opioid Receptor Desensitization The Faseb Journal. 21 |