Andrew T. Jacovina, Ph.D.

Affiliations: 
2000 Weill Cornell Medical College, New York, NY, United States 
Area:
Cell Biology, Neuroscience Biology, Molecular Biology
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"Andrew Jacovina"
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Katherine A. Hajjar grad student 2000 Weill Cornell Medical College
 (The regulation of annexin II gene expression and function during nerve growth factor-induced differentiation of PC -12 cells.)
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Publications

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Huang B, Deora AB, He KL, et al. (2011) Hypoxia-inducible factor-1 drives annexin A2 system-mediated perivascular fibrin clearance in oxygen-induced retinopathy in mice. Blood. 118: 2918-29
Jacovina AT, Deora AB, Ling Q, et al. (2009) Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis. The Journal of Clinical Investigation. 119: 3384-94
Romay-Penabad Z, Montiel-Manzano MG, Shilagard T, et al. (2009) Annexin A2 is involved in antiphospholipid antibody-mediated pathogenic effects in vitro and in vivo. Blood. 114: 3074-83
Deora AB, Kreitzer G, Jacovina AT, et al. (2004) An annexin 2 phosphorylation switch mediates p11-dependent translocation of annexin 2 to the cell surface Journal of Biological Chemistry. 279: 43411-43418
Ling Q, Jacovina AT, Deora A, et al. (2004) Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo. The Journal of Clinical Investigation. 113: 38-48
Brownstein C, Deora AB, Jacovina AT, et al. (2004) Annexin II mediates plasminogen-dependent matrix invasion by human monocytes: enhanced expression by macrophages. Blood. 103: 317-24
Jacovina AT, Zhong F, Khazanova E, et al. (2001) Neuritogenesis and the nerve growth factor-induced differentiation of PC-12 cells requires annexin II-mediated plasmin generation. The Journal of Biological Chemistry. 276: 49350-8
Menell JS, Cesarman GM, Jacovina AT, et al. (1999) Annexin II and bleeding in acute promyelocytic leukemia. The New England Journal of Medicine. 340: 994-1004
Hajjar KA, Jacovina AT. (1998) Modulation of annexin II by homocysteine: implications for atherothrombosis. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 46: 364-9
Hajjar KA, Mauri L, Jacovina AT, et al. (1998) Tissue plasminogen activator binding to the annexin II tail domain. Direct modulation by homocysteine. The Journal of Biological Chemistry. 273: 9987-93
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