Tsutomu Sasaki, Ph.D.

Affiliations: 
2007 University of Virginia, Charlottesville, VA 
Area:
Molecular Biology, Neuroscience Biology
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"Tsutomu Sasaki"
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Heidi Scrable grad student 2007 UVA
 (SIRT1 phosphorylation and cell proliferation.)
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Publications

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Hosooka T, Hosokawa Y, Matsugi K, et al. (2020) The PDK1-FoxO1 signaling in adipocytes controls systemic insulin sensitivity through the 5-lipoxygenase-leukotriene B axis. Proceedings of the National Academy of Sciences of the United States of America
Matsui S, Sasaki T, Kohno D, et al. (2018) Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice. Nature Communications. 9: 4604
Gulshan M, Yaku K, Okabe K, et al. (2018) Overexpression of Nmnat3 efficiently increases NAD and NGD levels and ameliorates age-associated insulin resistance. Aging Cell. e12798
Sasaki T, Numano R, Yokota-Hashimoto H, et al. (2018) A central-acting connexin inhibitor, INI-0602, prevents high-fat diet-induced feeding pattern disturbances and obesity in mice. Molecular Brain. 11: 28
Fukunaka A, Fukada T, Bhin J, et al. (2017) Zinc transporter ZIP13 suppresses beige adipocyte biogenesis and energy expenditure by regulating C/EBP-β expression. Plos Genetics. 13: e1006950
Iwakoshi-Ukena E, Shikano K, Kondo K, et al. (2017) Neurosecretory protein GL stimulates food intake, de novo lipogenesis, and onset of obesity. Elife. 6
Sasaki T. (2015) Age-Associated Weight Gain, Leptin, and SIRT1: A Possible Role for Hypothalamic SIRT1 in the Prevention of Weight Gain and Aging through Modulation of Leptin Sensitivity. Frontiers in Endocrinology. 6: 109
Sasaki T, Kuroko M, Sekine S, et al. (2015) Overexpression of insulin receptor partially improves obese and diabetic phenotypes in db/db mice. Endocrine Journal
Sasaki T, Hiraga H, Yokota-Hashimoto H, et al. (2015) Miglitol protects against age-dependent weight gain in mice: A potential role of increased UCP1 content in brown adipose tissue [Rapid Communication]. Endocrine Journal. 62: 469-73
Kohno D, Lee S, Harper MJ, et al. (2014) Dnmt3a in Sim1 neurons is necessary for normal energy homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15288-96
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