Dennis B. McKay

Affiliations: 
Ohio State University, Columbus, Columbus, OH 
Area:
Pharmacology, Neuroscience Biology
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"Dennis McKay"
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Children

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R. B. Free grad student 2002 Ohio State
Bryan W. Wenger grad student 2003 Ohio State
Bitna Yi grad student 2013 Ohio State
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Publications

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Yi B, Long S, González-Cestari TF, et al. (2013) Discovery of benzamide analogs as negative allosteric modulators of human neuronal nicotinic receptors: pharmacophore modeling and structure-activity relationship studies. Bioorganic & Medicinal Chemistry. 21: 4730-43
Still PC, Yi B, González-Cestari TF, et al. (2013) Alkaloids from Microcos paniculata with cytotoxic and nicotinic receptor antagonistic activities. Journal of Natural Products. 76: 243-9
Henderson BJ, González-Cestari TF, Yi B, et al. (2012) Defining the putative inhibitory site for a selective negative allosteric modulator of human α4β2 neuronal nicotinic receptors. Acs Chemical Neuroscience. 3: 682-92
Henderson BJ, Orac CM, Maciagiewicz I, et al. (2012) 3D-QSAR and 3D-QSSR models of negative allosteric modulators facilitate the design of a novel selective antagonist of human α4β2 neuronal nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 22: 1797-813
Mahasenan KV, Pavlovicz RE, Henderson BJ, et al. (2011) Discovery of Novel α4β2 Neuronal Nicotinic Receptor Modulators through Structure-Based Virtual Screening. Acs Medicinal Chemistry Letters. 2: 855-60
Henderson BJ, Carper DJ, González-Cestari TF, et al. (2011) Structure-activity relationship studies of sulfonylpiperazine analogues as novel negative allosteric modulators of human neuronal nicotinic receptors. Journal of Medicinal Chemistry. 54: 8681-92
Pavlovicz RE, Henderson BJ, Bonnell AB, et al. (2011) Identification of a negative allosteric site on human α4β2 and α3β4 neuronal nicotinic acetylcholine receptors. Plos One. 6: e24949
Potaros T, Phornchirasilp S, McKay SB, et al. (2011) Evidence for the involvement of adenomatous polyposis coli (APC) protein in maintaining cellular distributions of α3β4 nicotinic receptors. Neuroscience Letters. 489: 105-9
Henderson BJ, Pavlovicz RE, Allen JD, et al. (2010) Negative allosteric modulators that target human alpha4beta2 neuronal nicotinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 334: 761-74
González-Cestari TF, Henderson BJ, Pavlovicz RE, et al. (2009) Effect of novel negative allosteric modulators of neuronal nicotinic receptors on cells expressing native and recombinant nicotinic receptors: implications for drug discovery. The Journal of Pharmacology and Experimental Therapeutics. 328: 504-15
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