Dana S. Perkins, Ph.D.
Affiliations: | 2002 | University of Maryland School of Medicine, Baltimore, MD, United States |
Area:
Microbiology Biology, Neuroscience BiologyGoogle:
"Dana Perkins"Mean distance: 30533.1
Parents
Sign in to add mentor| Laure Aurelian | grad student | 2002 | University of Maryland Medical School | |
| (Anti-apoptotic activity of the herpes simplex virus type 2 gene ICP10 PK: Implications for therapy of neurological disorders that involve apoptosis.) | ||||
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Publications
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| Perkins D, Gyure KA, Pereira EF, et al. (2003) Herpes simplex virus type 1-induced encephalitis has an apoptotic component associated with activation of c-Jun N-terminal kinase. Journal of Neurovirology. 9: 101-11 |
| Perkins D, Pereira EFR, Aurelian L. (2003) The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) functions as a dominant regulator of apoptosis in hippocampal neurons involving activation of the ERK survival pathway and upregulation of the antiapoptotic protein bag-1 Journal of Virology. 77: 1292-1305 |
| Perkins D. (2003) Targeting apoptosis in neurological disease using the herpes simplex virus. Journal of Cellular and Molecular Medicine. 6: 341-56 |
| Perkins D, Yu Y, Bambrick LL, et al. (2002) Expression of herpes simplex virus type 2 protein ICP10 PK rescues neurons from apoptosis due to serum deprivation or genetic defects. Experimental Neurology. 174: 118-22 |
| Perkins D, Pereira EFR, Gober M, et al. (2002) The herpes simplex virus type 2 r1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway Journal of Virology. 76: 1435-1449 |