David B. Weiner, Ph.D.

Affiliations: 
Pathology & Laboratory Medicine University of Pennsylvania, Philadelphia, PA, United States 
Area:
DNA vaccine, HIV
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Alfred Hyoungju Kim research assistant 1995-1997 University of Pennsylvania School of Medicine
Michael A. Chattergoon grad student 2003 Penn
Dominick J. Laddy grad student 2008 Penn
Kimberly A. Kraynyak grad student 2009 Penn
Lauren A. Hirao grad student 2010 Penn
Krystle A. Kuhs grad student 2011 Penn
Nyamekye Obeng-Adjei grad student 2013 Penn
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Publications

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Shore ND, Morrow MP, McMullan T, et al. (2020) CD8 T Cells Impact Rising PSA in Biochemically Relapsed Cancer Patients Using Immunotherapy Targeting Tumor-Associated Antigens. Molecular Therapy : the Journal of the American Society of Gene Therapy
Muthumani K, Falzarano D, Reuschel EL, et al. (2015) A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates. Science Translational Medicine. 7: 301ra132
Scott VL, Villarreal DO, Hutnick NA, et al. (2015) DNA vaccines targeting heavy chain C-terminal fragments of Clostridium botulinum neurotoxin serotypes A, B, and E induce potent humoral and cellular immunity and provide protection from lethal toxin challenge. Human Vaccines & Immunotherapeutics. 11: 1961-71
Scott VL, Patel A, Villarreal DO, et al. (2015) Novel synthetic plasmid and doggybone™ DNA vaccines induce neutralizing antibodies and provide protection from lethal influenza challenge in mice. Human Vaccines & Immunotherapeutics. 0
Villarreal DO, Siefert RJ, Weiner DB. (2015) Alarmin IL-33 elicits potent TB-specific cell-mediated responses. Human Vaccines & Immunotherapeutics. 11: 1954-60
Wise MC, Hutnick NA, Pollara J, et al. (2015) An enhanced synthetic multi-clade DNA prime induces improved cross-clade reactive functional antibodies when combined with an adjuvanted protein boost in non-human primates. Journal of Virology
Kutzler MA, Wise MC, Hutnick NA, et al. (2015) Chemokine-adjuvanted electroporated DNA vaccine induces substantial protection from simian immunodeficiency virus vaginal challenge. Mucosal Immunology
Villarreal DO, Svoronos N, Wise MC, et al. (2015) Molecular adjuvant IL-33 enhances the potency of a DNA vaccine in a lethal challenge model. Vaccine
Wu SJ, Villarreal DO, Shedlock DJ, et al. (2015) Synthetic DNA approach to cytomegalovirus vaccine/immune therapy. Advances in Experimental Medicine and Biology. 848: 131-48
Flingai S, Plummer EM, Patel A, et al. (2015) Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy Scientific Reports. 5
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