Channing Yu, Ph.D.

Affiliations: 
2003 Harvard University, Cambridge, MA, United States 
Area:
Genetics, Molecular Biology
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"Channing Yu"
Mean distance: 35622
 

Parents

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Stuart H. Orkin grad student 2003 Harvard
 (Genetics and genomics of GATA-1 function in hematopoiesis.)
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Publications

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Li Z, Godinho FJ, Klusmann JH, et al. (2005) Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1. Nature Genetics. 37: 613-9
Humbles AA, Lloyd CM, McMillan SJ, et al. (2004) A critical role for eosinophils in allergic airways remodeling. Science (New York, N.Y.). 305: 1776-9
Li Z, Godinho F, Garriga-Canut M, et al. (2004) Developmental Stage-Selective Effect of Somatically Mutated GATA-1 in Down Syndrome AML M7--a Potential Basis for Transient Myeloproliferative Disorder. Blood. 104: 463-463
Yu C, Niakan KK, Matsushita M, et al. (2002) X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction. Blood. 100: 2040-5
Yu C, Cantor AB, Yang H, et al. (2002) Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo. The Journal of Experimental Medicine. 195: 1387-95
Han AP, Yu C, Lu L, et al. (2001) Heme-regulated eIF2alpha kinase (HRI) is required for translational regulation and survival of erythroid precursors in iron deficiency. The Embo Journal. 20: 6909-18
Zhang P, Zhang X, Iwama A, et al. (2000) PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding. Blood. 96: 2641-8
Shirihai OS, Gregory T, Yu C, et al. (2000) ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation. The Embo Journal. 19: 2492-502
Gregory T, Yu C, Ma A, et al. (1999) GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-x(L) expression Blood. 94: 87-96
Gregory T, Yu C, Ma A, et al. (1999) GATA-1 and Erythropoietin Cooperate to Promote Erythroid Cell Survival by Regulating bcl-xL Expression Blood. 94: 87-96
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