Thomas S. Wehrman, Ph.D.

Affiliations: 
2004 Stanford University, Palo Alto, CA 
Area:
Molecular Biology
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"Thomas Wehrman"
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Helen M. Blau grad student 2004 Stanford
 (Development of protein complementation assays and small interfering RNA libraries for protein interactions, localization, and gene function.)
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Publications

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Bassoni DL, Raab WJ, Achacoso PL, et al. (2012) Measurements of β-arrestin recruitment to activated seven transmembrane receptors using enzyme complementation. Methods in Molecular Biology (Clifton, N.J.). 897: 181-203
von Degenfeld G, Wehrman TS, Blau HM. (2009) Imaging beta-galactosidase activity in vivo using sequential reporter-enzyme luminescence. Methods in Molecular Biology (Clifton, N.J.). 574: 249-59
Hammer MM, Wehrman TS, Blau HM. (2007) A novel enzyme complementation-based assay for monitoring G-protein-coupled receptor internalization. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3827-34
von Degenfeld G, Wehrman TS, Hammer MM, et al. (2007) A universal technology for monitoring G-protein-coupled receptor activation in vitro and noninvasively in live animals. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3819-26
Wehrman TS, Raab WJ, Casipit CL, et al. (2006) A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions. Proceedings of the National Academy of Sciences of the United States of America. 103: 19063-8
Wehrman TS, von Degenfeld G, Krutzik PO, et al. (2006) Luminescent imaging of beta-galactosidase activity in living subjects using sequential reporter-enzyme luminescence. Nature Methods. 3: 295-301
Sen GL, Wehrman TS, Blau HM. (2005) mRNA translation is not a prerequisite for small interfering RNA-mediated mRNA cleavage. Differentiation; Research in Biological Diversity. 73: 287-93
Wehrman TS, Casipit CL, Gewertz NM, et al. (2005) Enzymatic detection of protein translocation. Nature Methods. 2: 521-7
Sen G, Wehrman TS, Myers JW, et al. (2004) Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nature Genetics. 36: 183-9
Wehrman T, Kleaveland B, Her JH, et al. (2002) Protein-protein interactions monitored in mammalian cells via complementation of beta -lactamase enzyme fragments. Proceedings of the National Academy of Sciences of the United States of America. 99: 3469-74
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