Prabhakar D. Borge, Ph.D.

Affiliations: 
2003 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biochemistry, Molecular Biology
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"Prabhakar Borge"
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Parents

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Bryan A. Wolf grad student 2003 Penn
 (IRS -1 inhibition of SERCA: A potential molecular interaction mechanism for regulation of insulin secretion and calcium homeostasis in pancreatic beta-cells.)
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Publications

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Borge PD, Wolf BA. (2003) Insulin receptor substrate 1 regulation of sarco-endoplasmic reticulum calcium ATPase 3 in insulin-secreting beta-cells. The Journal of Biological Chemistry. 278: 11359-68
Borge PD, Moibi J, Greene SR, et al. (2002) Insulin receptor signaling and sarco/endoplasmic reticulum calcium ATPase in beta-cells. Diabetes. 51: S427-33
Xu GG, Gao ZY, Borge PD, et al. (2000) Insulin regulation of beta-cell function involves a feedback loop on SERCA gene expression, Ca(2+) homeostasis, and insulin expression and secretion. Biochemistry. 39: 14912-9
Xu GG, Gao ZY, Borge PD, et al. (1999) Insulin receptor substrate 1-induced inhibition of endoplasmic reticulum Ca2+ uptake in beta-cells. Autocrine regulation of intracellular ca2+ homeostasis and insulin secretion. The Journal of Biological Chemistry. 274: 18067-74
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