Roger L. Papke

Affiliations: 
University of Florida, Gainesville, Gainesville, FL, United States 
Area:
neuronal nicotinic acetylcholine receptors
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"Roger Papke"
Mean distance: 14.29 (cluster 11)
 
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Publications

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Bagdas D, Wilkerson JL, Kulkarni A, et al. (2016) The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain. British Journal of Pharmacology
Horenstein NA, Papke RL, Kulkarni AR, et al. (2016) Critical molecular determinants of α7 nicotinic acetylcholine receptor allosteric activation: separation of direct allosteric activation and positive allosteric modulation. The Journal of Biological Chemistry
Quadri M, Papke RL, Horenstein NA. (2015) Dissection of N,N-diethyl-N'-phenylpiperazines as α7 nicotinic receptor silent agonists. Bioorganic & Medicinal Chemistry
Papke RL, Horenstein NA, Stokes C. (2015) Nicotinic Activity of Arecoline, the Psychoactive Element of "Betel Nuts", Suggests a Basis for Habitual Use and Anti-Inflammatory Activity. Plos One. 10: e0140907
van Maanen MA, Papke RL, Koopman FA, et al. (2015) Two novel α7 nicotinic acetylcholine receptor ligands: in vitro properties and their efficacy in collagen-induced arthritis in mice. Plos One. 10: e0116227
Papke RL, Bagdas D, Kulkarni AR, et al. (2015) The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor. Neuropharmacology. 91: 34-42
Bordia T, McGregor M, Papke RL, et al. (2015) The α7 nicotinic receptor agonist ABT-107 protects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions. Experimental Neurology. 263: 277-84
Stokes C, Treinin M, Papke RL. (2015) Looking below the surface of nicotinic acetylcholine receptors Trends in Pharmacological Sciences. 36: 514-523
Papke RL, Chojnacka K, Horenstein NA. (2014) The minimal pharmacophore for silent agonism of the α7 nicotinic acetylcholine receptor. The Journal of Pharmacology and Experimental Therapeutics. 350: 665-80
Ponzoni L, Braida D, Pucci L, et al. (2014) The cytisine derivatives, CC4 and CC26, reduce nicotine-induced conditioned place preference in zebrafish by acting on heteromeric neuronal nicotinic acetylcholine receptors. Psychopharmacology. 231: 4681-93
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